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http://dx.doi.org/10.1001/jama.2025.6522 | DOI Listing |
Int J Eat Disord
September 2025
Department of Psychology, Wesleyan University, Middletown, Connecticut, USA.
Objectives: Generative Artificial Intelligence (AI) could transform how science is conducted, supporting researchers with writing, coding, peer review, and evidence synthesis. However, it is not yet known how eating disorder researchers utilize generative AI, and uncertainty remains regarding its safe, ethical, and transparent use. The Executive Committee of the International Journal of Eating Disorders disseminated a survey for eating disorder researchers investigating their practices and perspectives on generative AI, with the goal of informing guidelines on appropriate AI use for authors, reviewers, and editors.
View Article and Find Full Text PDFNutr J
September 2025
Department of Geriatric, The First Hospital of China Medical University, No. 155 Nanjing North Street, Heping Ward, Shenyang, 110001, China.
Objective: This study analyzed data from the US population to examine how oral microbiome diversity and diet quality individually and synergistically affect frailty.
Methods: This study included 6,283 participants aged 20 years or older from the 2009-2010 and 2011-2012 NHANES cycles. A frailty index (FI) consisting of 36 items was developed, with items related to nutritional status excluded.
Diabetes Metab Res Rev
September 2025
Interdisciplinary Department of Medicine, School of Medicine, University of Bari 'Aldo Moro', Bari, Italy.
Overweight and obesity represent common chronic metabolic disorders in the general population, and observed trends describe a substantial growth in the prevalence of weight excess also among individuals with type 1 diabetes (T1D), the so-called 'lean phenotype' of diabetes. The sharp rise of weight excess and obesity-related cardio-nephron-metabolic burdens observed in T2D is expected to produce similar consequences in T1D, leading to the urgent need to endorse therapeutic protocols as in most parts of the World no adjunctive treatments are approved for T1D, making weight excess management challenging in these individuals. The notable results shown by newer glucagon-like peptide 1 receptor agonists (GLP-1RAs) and emerging dual agonists, especially while managing cardio-metabolic burdens, in T2D have encouraged fervent anecdotal and non-anecdotal research also in T1D, indicating that non-insulin injective agents can be effective and safe.
View Article and Find Full Text PDFClin Gastroenterol Hepatol
August 2025
Vatche and Tamar Manoukian Division of Digestive Diseases, University of California, Los Angeles; Goodman Luskin Microbiome Center, University of California, Los Angeles; G. Oppenheimer Center for Neurobiology of Stress and Resilience, University of California, Los Angeles; David Geffen School of Me
Background: Despite significant advances in the understanding of the pathogenesis of obesity and influencing factors, its prevalence continues to increase at an alarming rate. Social determinants of health (SDOH) encompass a broad range of psychosocial and environmental factors, including economic stability, education, access to healthcare, social support, isolation, neighborhood disadvantage, discrimination, early life adversity, and stress, all of which have been recognized to significantly increase the risk of obesity.
Aim: This review aims to elucidate the intricate relationship between SDOH and biological mechanisms related to the brain-gut-microbiome (BGM) system that lead to altered eating behaviors and obesity.
Semin Arthritis Rheum
August 2025
Division of Rheumatology, Mayo Clinic, 200 First St SW, Rochester, MN 55905, USA; Department of Quantitative Health Sciences, Mayo Clinic, 200 First St SW, Rochester, MN 55905, USA. Electronic address:
Objectives: We aimed to determine the degree to which a healthy dietary pattern is associated with incident rheumatoid arthritis (RA).
Methods: We registered this systematic review and meta-analysis in PROSPERO (CRD42025645056). Inclusion criteria were validated diet (anti-inflammatory, Mediterranean, Dietary Approaches to Stop Hypertension (DASH), and/or healthy eating index [HEI]); validated RA definition; dietary exposure preceding RA; and randomized controlled trial, cohort, or case-control design.