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Objective: As the global population ages and traditional family support structures decline, mental health issues-particularly anxiety-among widowed older adults have become increasingly prevalent. Studies have shown a positive correlation between ageism and anxiety disorders in older bereaved individuals, but the underlying mechanism by which ageism affects anxiety in this population has not yet been clarified. This study aimed to examine whether loneliness mediates the relationship between age discrimination and anxiety disorders, and whether cognitive functioning moderates this mediation.
Methods: A random sampling approach was used to select 406 older adults who have lost their spouse from Shenyang, China. The Generalized Anxiety Scale (GAD-7), Perceived Age Discrimination Scale (PAD), UCLA Loneliness Scale (UCLA-LS), and Alzheimer's Disease 8-Item Screening Instrument (AD-8) were used to assess the status of anxiety, ageism, loneliness, and cognitive functioning, respectively. Moderated mediation models were analyzed by SPSS PROCESS version 4.0 software.
Results: Age discrimination had a significant direct effect on anxiety in widowed individuals in later life. Loneliness partially mediated the effect of age discrimination knowledge on anxiety. In addition, the second half of the path of the indirect effect was moderated by cognitive functioning. The indirect effect of loneliness on anxiety was enhanced when cognitive functioning was poor.
Conclusion: Loneliness enhances the positive association between ageism and anxiety in widowed older adults, in which cognitive functioning plays a moderating role. These findings suggest the need for targeted psychosocial interventions that prioritize cognitive health and social engagement to reduce anxiety among bereaved older adults.
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http://dx.doi.org/10.3389/fpsyg.2025.1624197 | DOI Listing |
JCI Insight
September 2025
Diabetes & Metabolism Research Center, University of Utah, Salt Lake City, United States of America.
Impaired muscle regrowth in aging is underpinned by reduced pro-inflammatory macrophage function and subsequently impaired muscle cellular remodeling. Macrophage phenotype is metabolically controlled through TCA intermediate accumulation and activation of HIF1A. We hypothesized that transient hypoxia following disuse in old mice would enhance macrophage metabolic inflammatory function thereby improving muscle cellular remodeling and recovery.
View Article and Find Full Text PDFJ Med Internet Res
September 2025
Institute of Social Medicine, Occupational Health and Public Health (ISAP), Medical Faculty, University of Leipzig, Leipzig, Germany.
Background: The loss of a loved one is a common yet stressful event in later life. Internet- and mobile-based interventions have been proposed as an effective treatment approach for individuals with prolonged grief.
Objective: The AgE-health study aimed to investigate the efficacy of an eHealth intervention, trauer@ktiv, in reducing prolonged grief symptoms in a sample of older adults.
Soc Work Public Health
September 2025
Department of Healthcare Management, Çankırı Karatekin University, Çankırı, Türkiye.
This study investigates socioeconomic disparities in chronic respiratory diseases and the factors contributing to these inequalities, using data from the 2019 Turkish Health Survey. Multivariate logistic regression and Oaxaca-Blinder decomposition analyses reveal that 13.10% of adults aged 25 and older in Turkey suffer from chronic respiratory diseases, with a significantly higher prevalence among lower socioeconomic status (SES) individuals.
View Article and Find Full Text PDFJASA Express Lett
September 2025
Department of Audiology and Speech-Language Pathology, University of North Texas, Denton, Texas 76201,
Misophonia is a condition characterized by intense negative emotional reactions to trigger sounds and related stimuli. In this study, adult listeners (N = 15) with a self-reported history of misophonia symptoms and a control group without misophonia (N = 15) completed listening judgements of recorded misophonia trigger stimuli using a standard scale. Participants also completed an established questionnaire of misophonia symptoms, the Misophonia Questionnaire (MQ).
View Article and Find Full Text PDFJAMA Netw Open
September 2025
Department of Psychiatry, Psychosomatics, and Psychotherapy, University of Lübeck, Lübeck, Germany.
Importance: Patients with inflammatory rheumatic diseases (IRDs) frequently experience psychological distress; however, access to psychological support remains limited.
Objective: To investigate the effectiveness of a digital psychological intervention for individuals with IRDs.
Design, Setting, And Participants: Participants aged 18 years or older were recruited across Germany between February 22 and June 4, 2024, if they had been diagnosed with rheumatoid arthritis, psoriatic arthritis, or systemic lupus erythematosus and reported psychological distress and reduced quality of life.