Culture-Negative Peritonitis and the Latest Diagnostic Techniques.

Kidney Dis (Basel)

Department of Nephrology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.

Published: December 2024


Category Ranking

98%

Total Visits

921

Avg Visit Duration

2 minutes

Citations

20

Article Abstract

Background: Peritonitis is a common and serious complication of peritoneal dialysis that results in considerable morbidity, mortality, and increased healthcare costs. A positive culture-based microorganism test is one of the main criteria for the diagnosis of peritonitis. However, the rates of positive bacterial culture remain quite low.

Summary: Peritonitis is a frequently encountered and consequential complication of peritoneal dialysis that poses a significant clinical burden in terms of morbidity, mortality, and healthcare expenditure. The reliance on culture-positive microbiological tests as a cornerstone of peritonitis diagnosis often results in a relatively low rate of positive results.

Key Messages: This article aimed to present a comprehensive synthesis and critical analysis of the most recent diagnostic modalities used to identify peritonitis-associated pathogens in peritoneal dialysis. Emphasis was placed on both direct diagnostic tools for pathogen identification and rapid detection methodologies that facilitate expedited pathogen diagnosis in peritonitis.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC12215107PMC
http://dx.doi.org/10.1159/000542870DOI Listing

Publication Analysis

Top Keywords

peritoneal dialysis
12
complication peritoneal
8
morbidity mortality
8
diagnosis peritonitis
8
peritonitis
5
culture-negative peritonitis
4
peritonitis latest
4
latest diagnostic
4
diagnostic techniques
4
techniques background
4

Similar Publications

Peritoneal dialysis (PD) and hemodialysis (HD) are the two primary renal replacement therapies for patients with end-stage renal disease (ESRD). While PD is an effective and convenient modality, long-term use can lead to ultrafiltration failure, recurrent peritonitis, and progressive structural alterations in the peritoneal membrane, necessitating a transition to HD. In recent years, rather than a complete transition, the combined use of PD and HD has emerged as a viable alternative, offering potential advantages for selected patient populations.

View Article and Find Full Text PDF

Objectives: To systematically review evidence on the safety and effectiveness of contraceptive use among women with chronic kidney disease (CKD).

Study Design: We searched for articles in multiple databases from database inception through December 12, 2022, that assessed safety and effectiveness of contraceptive use among women with CKD; all study designs were included. We extracted data from included articles; for studies that were not case series or case reports, we assessed risk of bias and determined certainty of evidence for each outcome.

View Article and Find Full Text PDF

Obstructive Sleep Apnea in Adult Dialysis Patients: A Review.

Respir Med

September 2025

Department of Internal Medicine, Staten Island University Hospital, Northwell Health, Staten Island, NY, USA.

Obstructive sleep apnea (OSA) is an extremely common but underdiagnosed problem in adults receiving dialysis therapy. Patients with end-stage kidney disease (ESKD) on hemodialysis or peritoneal dialysis have a higher prevalence of OSA compared to the general population (1-3). This condition carries significant clinical implications, contributing to impaired sleep quality, daytime fatigue, and elevated cardiovascular risk if left untreated (4,5).

View Article and Find Full Text PDF

Objective: Upper-extremity arteriovenous (AV) access often requires re-intervention. However, the frequency of re-interventions and subsequent access failure is not well-characterized. Our goal was to evaluate the frequency and type of re-interventions, risk-factors, and outcomes after AV access creation.

View Article and Find Full Text PDF

Background: The triglyceride-glucose-body mass index (TyG-BMI) is a simple indicator of insulin resistance and is linked to an elevated risk of mortality. Nevertheless, limited research has explored the associations between the TyG-BMI and all-cause and cardiovascular mortality in patients undergoing peritoneal dialysis (PD).

Methods: Patients initiating PD treatment at the Tianjin First Central Hospital's Nephrology Department from July 2013 to February 2024 had triglycerides, fasting blood glucose, height, and weight measured at baseline and monthly during follow-up.

View Article and Find Full Text PDF