98%
921
2 minutes
20
Download full-text PDF |
Source |
---|---|
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC12380596 | PMC |
http://dx.doi.org/10.1038/s41375-025-02675-7 | DOI Listing |
Cancer Rep (Hoboken)
September 2025
ENT and Head and Neck Research Center and Department, the Five Senses Health Institute, School of Medicine, Iran University of Medical Sciences, Tehran, Iran.
Objective: To present a case of metastatic endometrial carcinosarcoma (ECS) with a long-term complete response to chemotherapy using a paclitaxel and carboplatin regimen.
Case Report: A 47-year-old premenopausal woman was diagnosed with a large, advanced intrauterine tumor. She underwent a total abdominal hysterectomy with bilateral salpingo-oophorectomy.
PLoS One
September 2025
Department of Biomedicine, Health and Life Convergence Sciences, BK21 Four, College of Pharmacy, Mokpo National University, Muan, Republic of Korea.
Non-small cell lung cancer (NSCLC) is one of the leading causes of cancer-related deaths, remaining a significant challenge in terms of early detection, effective treatment, and improving patient survival rates. In this study, we investigated the anticancer mechanism of rubiarbonol B (Ru-B) and its derivative 3-O-acetylrubiarbonol B (ARu-B), a pentacyclic terpenoid in gefitinib (GEF)-sensitive and -resistant NSCLC HCC827 cells. Concentration- and time-dependent cytotoxicity was observed for both Ru-B and ARu-B.
View Article and Find Full Text PDFCureus
August 2025
General Surgery, Lahore General Hospital, Lahore, PAK.
Urinary bladder cancer contributes significantly to the global cancer burden and is more prevalent in the developed world. We present the case of a 54-year-old male smoker who underwent transurethral resection of bladder tumor and consequent trimodality therapy (induction chemotherapy followed by concomitant chemo-radiotherapy). His disease was staged at cT3N0M0.
View Article and Find Full Text PDFCureus
August 2025
Department of Gastrointestinal and Pediatric Surgery, Division of Reparative Medicine, Institute of Life Sciences, Graduate School of Medicine, Mie University, Tsu, JPN.
Conversion surgery is increasingly used for initially unresectable esophageal cancer patients responding to induction therapy. The integration of immune checkpoint inhibitors (ICIs) into standard chemotherapy regimens is expected to increase the number of patients undergoing this approach. However, ICIs can cause immune-related adverse events (irAEs), which are often difficult to diagnose in the postoperative setting.
View Article and Find Full Text PDFCureus
August 2025
Department of Otolaryngology - Head and Neck Surgery, China Medical University Hospital, Taichung, TWN.
Synchronous malignancies involving the oropharynx and thyroid gland are rare. We report the case of a 52-year-old female diagnosed with human papillomavirus (HPV)-associated oropharyngeal squamous cell carcinoma (OPSCC) with a concurrent, clinically occult papillary thyroid carcinoma (PTC). The patient initially presented with HPV-associated OPSCC and concerns for cervical lymphadenopathy, presumed to be linked to regional metastasis from the oropharyngeal primary.
View Article and Find Full Text PDF