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The Human Immunodeficiency Virus, or HIV, is a retrovirus which aims at CD4 cells in particular to destroy the body's natural defenses along with impair its capacity for fighting off illness plus ailments. In this circumstance we suggested a Photonic Crystal Fiber (PCF) sensor for detection of this lethal virus. Our intended sensor exhibits Max Relative Sensitivity (RS) 95.2% & 95% for x & y axis correspondingly when f = 3.0 THz. It also impresses us with minimal Confinement Loss (CL) of 1.06 × 10-7 & 2.04 × 10-7dB/m plus Effective Material Loss (EML) of 0.0078 & 0.0110 cm-1 in that order for x & y axis. Initial detection alongside prompt cures for HIV are made feasible by the remarkable efficacy of PCF biosensor observations in this regard. PCF gadgets offer rapid, non-invasive medical diagnosis, which simplifies the need for further evaluation & allows for an assessment of a condition's progression as it progresses. Precise assessment may be beneficial when investigating advancements that improve worldwide identification and therapeutic choices. It is possible that the rapid identification of these harmful microbes was made possible by the remarkable identifying ability provided by the new PCF. In conclusion, healthcare offers a plethora of opportunity.
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC12212498 | PMC |
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0327357 | PLOS |
Biosensors (Basel)
August 2025
Department of Electrical and Electronics Engineering, Ariel University, Ariel 40700, Israel.
This numerical study introduces a surface plasmon resonance (SPR)-based biosensor utilizing a kagome lattice-inspired hollow core photonic crystal fiber (PCF) for the highly sensitive detection of various blood biomarkers and analytical components. The sensor is designed to detect key blood biomarkers such as water, glucose, plasma, and hemoglobin (Hb), as well as analytical targets including krypton, sylgard, ethanol, polyacrylamide (PA), and bovine serum albumin (BSA), by monitoring shifts in the resonance wavelength (RW). A dual-polarization approach is employed by analyzing both transverse magnetic (TM) and transverse electric (TE) modes.
View Article and Find Full Text PDFAdv Mater
August 2025
Key Laboratory of Quantum State Construction and Manipulation (Ministry of Education), School of Physics, Renmin University of China, Beijing, 100872, China.
The integration of 2D materials with optical fibers enables multifunctional fiber devices, such as polarizers, modulators, and sensors. Recent advances in direct vapor deposition growth further enhance light-2D material interactions to centimeter-scale lengths, overcoming the micrometer-scale limitations of transferred 2D materials. However, conventional methods for growing 2D materials in fibers typically produce isotropic material architectures due to uniform precursor deposition, limiting applications that require birefringence, such as a phase retarder.
View Article and Find Full Text PDFWe demonstrate a simple and straightforward photonic crystal fiber (PCF) sensor for voltage and comparatively higher refractive index (RI) sensing, incorporating the surface plasmon resonance (SPR) phenomenon for better and more reliable performance. The sensor contains three air holes; the central air hole is filled with an electric field-tunable nematic liquid crystal (NLC), while the remaining holes are filled with the analyte. Due to changes in the surrounding voltages, the RI of NLC varies, and the sensor exhibits excellent sensitivity of 6 nm/V and a resolution of 16.
View Article and Find Full Text PDFA photonic crystal fiber (PCF) sensor based on symmetric lattices filled with magnetic fluid (MF) was designed for sensing applications using surface plasmon resonance (SPR) technology. Using COMSOL multiphysics, we employed the finite element method (FEM) to investigate and optimize a range of structural parameters for the sensor. Subsequently, various structural parameters, such as gold film thickness and pore structure, were analyzed to assess their effects on performance.
View Article and Find Full Text PDFSci Rep
August 2025
Nano‑Photonics and Optoelectronics Research Laboratory (NORLab), Shahid Rajaee Teacher Training University, Tehran, Iran.
In this article, a surface plasmon resonance (SPR) sensor based on photonic crystal fiber (PCF) has been presented for use in detecting the concentration of sucrose solution. This sensor is expertly designed, drawing on the vertical pupil pattern found in the eyes of certain animals to optimize the concentration of the electromagnetic field at the center of the structure. The primary objective is achieving superior amplitude sensitivity (AS) while minimizing losses.
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