Category Ranking

98%

Total Visits

921

Avg Visit Duration

2 minutes

Citations

20

Article Abstract

Introduction: Prefrailty is common among community-dwelling older adults with diabetes and can lead to adverse health outcomes. With effective exercise interventions, prefrailty is reversible. However, there is a paucity of evidence regarding the effects of exercise interventions for prefrail older adults with diabetes. This study presents a study protocol for evaluating the effectiveness of an exercise intervention based on the Capacity, Opportunity and Motivation Behaviour (COM-B) model among community-dwelling prefrail older adults with diabetes.

Methods And Analysis: Using a randomised controlled trial design, a total of 100 community-dwelling prefrail older adults with diabetes will be allocated to either an intervention or a control group in a 1:1 ratio. Participants in the intervention group will receive a 16-week multicomponent exercise intervention based on the COM-B model, while those in the control group will receive usual diabetes care and general advice on physical activity. The primary outcome is frailty status, and the secondary outcomes include physical function, quality of life, depressive symptoms, self-efficacy for exercise and fasting blood glucose. Assessments will be conducted at baseline, week 8 and week 16.

Ethics And Dissemination: This study has been approved by the Ethics Committee of the First Affiliated Hospital of Chongqing Medical University (approval number: K2023-320). The findings will be submitted to a peer-reviewed journal for publication.

Trial Registration Number: ChiCTR2400082831.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC12211824PMC
http://dx.doi.org/10.1136/bmjopen-2025-098945DOI Listing

Publication Analysis

Top Keywords

older adults
20
prefrail older
16
adults diabetes
16
exercise intervention
12
intervention based
12
com-b model
12
community-dwelling prefrail
12
effects exercise
8
based com-b
8
model community-dwelling
8

Similar Publications

Background: Cerebrovascular reactivity reflects changes in cerebral blood flow in response to an acute stimulus and is reflective of the brain's ability to match blood flow to demand. Functional MRI with a breath-hold task can be used to elicit this vasoactive response, but data validity hinges on subject compliance. Determining breath-hold compliance often requires external monitoring equipment.

View Article and Find Full Text PDF

Perinatal stroke is a vascular injury occurring early in life, often resulting in motor deficits (hemiplegic cerebral palsy/HCP). Comorbidities may also include poor neuropsychological outcomes, such as deficits in memory. Previous studies have used resting state functional MRI (fMRI) to demonstrate that functional connectivity (FC) within hippocampal circuits is associated with memory function in typically developing controls (TDC) and in adults after stroke, but this is unexplored in perinatal stroke.

View Article and Find Full Text PDF

Cognitive function is a critical health indicator of older adults in later life. However, previous research has paid less attention to the impact of pre-retirement work-related characteristics on cognitive functions, especially in Asia. Thus, this study aims to examine the relationship between work-related factors and cognitive functions of the retired population, using Taiwan as an example.

View Article and Find Full Text PDF

Background: Poor hand dexterity may increase the risk of functional disability; however, few studies have examined the relationship between hand dexterity and incident functional disability. The aim of this study was to prospectively investigate the dose-response association of hand dexterity with incident functional disability in community-dwelling older adults.

Methods: This study included 1,069 older adults aged ≥65 years in Kasama City, Japan.

View Article and Find Full Text PDF

Background: Coronal wedge insoles are commonly prescribed to mitigate musculoskeletal disorders, yet their static-standing kinematic and kinetic effects on lower extremity joints remain insufficiently understood.

Methods: This cross-sectional experimental study included 15 healthy older adults (mean 64.9 ± 6.

View Article and Find Full Text PDF