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Introduction And Importance: Surgical methods to treat gastric cancer are quite straightforward. However, in rare cases of gastric cancer accompanied by a splenic mass that requires splenectomy, treatment options become much more complicated. Splenectomy can effectively treat splenic masses, but without adequate salvation of vessels, could increase the risk of ischemic necrosis if simultaneously performed with distal subtotal gastrectomy.
Case Presentation: The patient is a 40-year-old male diagnosed with cancer at the stomach angle. Abdominal CT also confirmed a huge mass in the spleen, suspected to be sclerosing angiomatoid nodular transformation (SANT). 3-dimensional CT angiography and RUS™ software were used to visualize the patient's intraabdominal anatomy before and throughout surgery. The robotic approach was used to incorporate said technologies while intricately preserving the short gastric vessels. Indocyanine green was injected intravenously to confirm adequate perfusion to the remnant stomach.
Clinical Discussion: Subtotal gastrectomy can be performed concurrently with splenectomy if the splenic and vascular anatomies allow for a safe splenectomy and preservation of the short gastric vessels. The feasibility of the operation should be confirmed by meticulous exploration of the patient's specific anatomy before and during surgery.
Conclusion: This report demonstrates a successful method to perform subtotal gastrectomy with splenectomy. Despite its complexity and time-consuming nature, this procedure can greatly benefit patients by allowing safe resections and maximal preservation of digestive functions, nutrition, and quality of life. As a result, we recommend that it be more readily considered when treating complex cases like this.
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http://dx.doi.org/10.1016/j.ijscr.2025.111558 | DOI Listing |
Fam Cancer
September 2025
Ambry Genetics, 1 Enterprise, Aliso Viejo, CA, 92656, USA.
Pathogenic variants in the APC gene are classically associated with autosomal dominant familial adenomatous polyposis (FAP), characterized by tens-to-thousands of colonic adenomatous polyps and a high-penetrance predisposition to colorectal cancer. More recently, specific PVs in the YY1 binding motif of APC promoter 1B have been associated with autosomal dominant gastric adenocarcinoma and proximal polyposis of the stomach (GAPPS), characterized by tens-to-thousands of fundic gland polyps and a predisposition to gastric cancer but which are only rarely associated with features consistent with FAP. Although management guidelines currently treat FAP and GAPPS as mutually exclusive conditions, the extent of phenotypic overlap is not well-characterized.
View Article and Find Full Text PDFAnticancer Res
September 2025
Division of Gastroenterological and General Surgery, Department of Surgery, Showa Medical University, Tokyo, Japan.
Background/aim: Pancreatectomy after gastrectomy has been reported as a risk factor for ischemic complications in the remnant stomach. Severe complications may arise if the remnant stomach develops impaired blood flow. Herein, we describe a case of pancreaticoduodenectomy (PD) following proximal gastrectomy (PG) in which indocyanine green (ICG) fluorescence was useful for evaluating remnant gastric perfusion.
View Article and Find Full Text PDFMedicine (Baltimore)
August 2025
Department of Medicine, Graduate School, Kyung Hee University, Seoul, Republic of Korea.
Rationale: Retroperitoneal fibrosis (RPF) is a rare fibroinflammatory condition that can lead to ureteral obstruction and renal dysfunction. While most cases are idiopathic, secondary causes including malignancies should be considered. RPF secondary to gastric cancer is extremely rare, with only a few cases reported.
View Article and Find Full Text PDFSurg Endosc
August 2025
Department of Gastrointestinal Surgery, Shanghai East Hospital, School of Medicine, Tongji University, Shanghai, 200120, China.
Background: The optimal reconstruction method after laparoscopic distal gastrectomy (LDG) for gastric cancer remains controversial. This study evaluates the novel approach of subtotal gastrectomy with preservation of a small remnant stomach (SRS) combined with uncut Roux-en-Y (URY) reconstruction, focusing on surgical feasibility, complications, and nutritional outcomes.
Methods: A retrospective analysis of patients undergoing LDG (2017-2023) was conducted.
Ann Surg
August 2025
Section of Gastrointestinal Surgery, Hospital del Mar, Department of Surgery, Universitat Autònoma de Barcelona, Hospital del Mar Medical Research Institute (IMIM), Barcelona, Spain.
Objective: To compare postoperative events and oncologic results between minimally invasive gastrectomy (MIG) and open gastrectomy (OG) in gastric cancer surgery.
Background: Evidence of the short- and long-term results of MIG is still limited.
Methods: A population-based cohort study included all patients undergoing elective gastric cancer resection with curative intent between 2014 and 2021 across 39 centers belonging to the EURECCA Spanish Registry.