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People with Parkinson's Disease (PD) often experience progressively worsening gait, including changes in how they turn around, as the disease progresses. Existing clinical rating tools are not capable of capturing hour-by-hour variations of PD symptoms, as they are confined to brief assessments within clinic settings, leaving gait performance outside these controlled environments unaccounted for. Measuring turning angles continuously and passively is a component step towards using gait characteristics as sensitive indicators of disease progression in PD. This paper presents a deep learning-based approach to automatically quantify turning angles by extracting 3D skeletons from videos and calculating the rotation of hip and knee joints. We utilise advanced human pose estimation models, Fastpose and Strided Transformer, on a total of 1386 turning video clips from 24 subjects (12 people with PD and 12 healthy control volunteers), trimmed from a PD dataset of unscripted free-living videos in a home-like setting (Turn-REMAP). We also curate a turning video dataset, Turn-H3.6M, from the public Human3.6M human pose benchmark with 3D groundtruth, to further validate our method. Previous gait research has primarily taken place in clinics or laboratories evaluating scripted gait outcomes, but this work focuses on free-living home settings where complexities exist, such as baggy clothing and poor lighting. Due to difficulties in obtaining accurate groundtruth data in a free-living setting, we quantise the angle into the nearest bin 45° based on the manual labelling of expert clinicians. Our method achieves a turning calculation accuracy of 41.6%, a Mean Absolute Error (MAE) of 34.7°, and a weighted precision (WPrec) of 68.3% for Turn-REMAP. On Turn-H3.6M, it achieves an accuracy of 73.5%, an MAE of 18.5°, and a WPrec of 86.2%. This is the first work to explore the use of single monocular camera data to quantify turns by PD patients in a home setting. All data and models are publicly available, providing a baseline for turning parameter measurement to promote future PD gait research.
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http://dx.doi.org/10.1016/j.artmed.2025.103194 | DOI Listing |
Qual Life Res
September 2025
Department of Physical Therapy, Rady Faculty of Health Sciences, College of Rehabilitation Sciences, University of Manitoba, Winnipeg, MB, Canada.
Purpose: The purpose was to identify how the ICECAP-A and ICECAP-O have been used with adults who have neurological health conditions.
Methods: Following the Joanna Briggs Institute framework, a scoping review was conducted, searching five databases (Scopus, CINAHL, MEDLINE, Embase, and PsycINFO). Studies were included if participants were adults (age 18+ years) with neurological health conditions, and ICECAP-A or ICECAP-O were used in the study.
Exp Gerontol
September 2025
Department of Psychology, Christ University, Bangalore, 560029, India.
J Vasc Interv Radiol
September 2025
Chief consultant, Heart failure clinic & Echocardiography, GKNM hospital, Coimbatore, India.
Mol Cells
September 2025
Department of Neuroscience, Kyung Hee University, Seoul, South Korea; Department of Physiology, Kyung Hee University School of Medicine, Seoul, South Korea. Electronic address:
Parkinson's disease (PD) is a progressive neurodegenerative disorder characterized by the loss of dopaminergic neurons and the accumulation of misfolded α-synuclein. Current treatments, including dopaminergic medications and deep brain stimulation (DBS), provide symptomatic relief but do not halt disease progression. Recent advances in molecular research have enabled the development of disease-modifying strategies targeting key pathogenic mechanisms, such as α-synuclein aggregation, mitochondrial dysfunction, and genetic mutations including LRRK2 and GBA1.
View Article and Find Full Text PDFNeurologia (Engl Ed)
September 2025
Servicio de Neurología, CHUAC, Complejo Universitario de A Coruña, A Coruña, Spain.
Introduction: One of the current challenges in Parkinson's disease (PD) and other movement disorders (MD) is how and when to apply palliative care. Aware of the scarce training and implementation of this type of approach, we propose some consensual recommendations for palliative care (PC) in order to improve the quality of life of patients and their environment.
Material And Methods: After a first phase of needs analysis through a survey carried out on Spanish neurologists and a review of the literature, we describe recommendations for action structured in: palliative care models, selection of the target population, when, where and how to implement the PC.