Category Ranking
98%
Total Visits
921
Avg Visit Duration
2 minutes
Citations
20
Article Abstract
A 46-year-old diabetic Vietnamese engineer presented with a 2-month fever and left foot swelling. Chest imaging showed bilateral nodules with right apical cavitation, prompting empirical anti-tuberculosis therapy. Despite positive Xpert MTB/RIF and 1 month of treatment, his condition worsened. Bronchoscopy culture isolated . Treatment with ceftazidime and trimethoprim-sulfamethoxazole led to complete recovery. Negative MGIT culture excluded tuberculosis co-infection. This case highlights the diagnostic challenge when melioidosis mimics tuberculosis in endemic regions, particularly in diabetic patients. Positive molecular tuberculosis tests may reflect the previous infection, emphasising the need for culture confirmation and clinical correlation.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC12197865 | PMC |
| http://dx.doi.org/10.1002/rcr2.70257 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Melioidosis presenting as septic arthritis in hip joint of a 60-year old patient: Findings from a hospital-based surveillance in Bangladesh.
J Infect Public Health
October 2025
International Centre for Diarrhoeal Disease Research, Bangladesh (icddr,b), Dhaka, Bangladesh. Electronic address:
Melioidosis is a fatal bacterial infection caused by a soil-borne bacterium Burkholderia pseudomallei. Pneumonia, localized abscess and acute septicemia are the most common clinical presentations for melioidosis. Septic arthritis is relatively uncommon clinical manifestation and may cause severe infection.
View Article and Find Full Text PDFCase Report: Genetic evolution of during treatment leading to antibiotic resistance and disease relapse.
Wellcome Open Res
July 2025
Faculty of Tropical Medicine, Mahidol Oxford Tropical Medicine Research Unit, Mahidol University, Bangkok, Thailand.
Background: Melioidosis is a significant yet neglected cause of sepsis in tropical regions, particularly in southeast Asia, with poor clinical outcomes. It is a growing threat with an expanding global footprint. The causative organism, , is intrinsically resistant to most first-line empiric antibiotic regimens, but acquired resistance to recommended antibiotics for this infection is uncommon.
View Article and Find Full Text PDFDisseminated Melioidosis from a Ruptured Infective Aortic Aneurysm and Pedal Ulcers to Septic Arthritis and Osteomyelitis: A Case Report.
Vasc Specialist Int
August 2025
Department of Vascular and Endovascular Surgery, SRM Institutes for Medical Science, Chennai, India.
(BP) is a gram-negative bacterium that causes melioidosis. Prolonged infection can lead to dissemination with rare presentations. A 65-year-old male presented with worsening back pain, persistent fever, and bilateral infected pedal ulcers.
View Article and Find Full Text PDFDeciphering the diversity, structure, and function of cycle-inhibiting factor in neuroinfection.
Sci Prog
August 2025
Department of Microbiology and Immunology, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand.
ObjectiveThis study aimed to characterize the genetic diversity, structural variation, and functional role of the cycle inhibiting factor (Cif) in , with a particular focus on its involvement in neuronal infections.MethodsWe analyzed the gene () from 1294 clinical isolates of using phylogenetic analysis and structural modeling to identify Cif variant types. Functional characterization of selected variants was performed using plaque formation assays in SH-SY5Y neuroblastoma cells.
View Article and Find Full Text PDFHereditary distal renal tubular acidosis with chronic granulomatous disease: a rare coincidence.
CEN Case Rep
August 2025
Incharge Division of Pediatric Nephrology, Department of Pediatrics, Maulana Azad Medical College and Lok Nayak Hospital, New Delhi, India.
The primary defect in distal renal tubular acidosis (dRTA) is impaired H ion secretion in the distal nephron, resulting in a normal anion gap metabolic acidosis. The solute carrier family 4-member 1 (SLC4A1) gene encodes the erythroid and renal anion exchanger 1 (AE1) protein for chloride-bicarbonate exchange. Mutations in the gene can result in hereditary dRTA, red blood cell membrane defect, and hemolytic anemia.
View Article and Find Full Text PDF