98%
921
2 minutes
20
Strabismus surgery is required for some cases with abducens nerve palsy (ANP) without spontaneous resolution; however, whether the surgical corrective effect for ANP is similar to that of concomitant esotropia (ET) remains unclear. This study compared the 1-year surgical outcomes of recession and resection (RR) between patients with ANP (ANP group, 11 patients) and those with concomitant ET (ET group, 33 patients). The target angle of RR for ANP was added by 5 prism diopters (Δ) compared to concomitant ET. The 1-year corrective effect was relatively lower in the ANP group than in the ET group (2.1 ± 0.7 Δ/mm vs. 2.6 ± 0.6 Δ/mm, P = 0.07), but the 3-month effect was similar (2.3 ± 0.6 Δ/mm vs. 2.6 ± 0.6 Δ/mm, P = 0.31) because significantly larger drift occurred in the ANP group than in the ET group (2.3 ± 2.2 Δ vs. 0.2 ± 2.7 Δ, P = 0.03). Motor success at 1 year was achieved in 90.9% of patients in both groups. Our findings suggested that the target angle of RR was suitable to add by 5 Δ in patients with ANP compared to concomitant ET in order to maintain a long-term favorable ocular position.
Download full-text PDF |
Source |
---|---|
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC12202793 | PMC |
http://dx.doi.org/10.1038/s41598-025-05310-8 | DOI Listing |
Cell Biol Int
September 2025
Department of Pharmacy, Birla Institute of Technology and Science Pilani, Pilani Campus, India.
Diabetic cardiomyopathy (DCM) is a progressive heart disorder associated with diabetes mellitus, leading to structural and functional cardiac abnormalities. The mechanisms responsible include renin-angiotensin-aldosterone (RAAS) activation, inflammation, apoptosis, and metabolic disturbances. Despite well-established epidemiological links, treatments for DCM are elusive.
View Article and Find Full Text PDFJ Ethnopharmacol
September 2025
School of Chinese Pharmacy, Beijing University of Chinese Medicine, Beijing, 102400, China. Electronic address:
Ethnopharmacological Relevance: Fever is a prevalent clinical symptom and is usually caused by inflammation or infection. Persistent high fever can lead to delirium, coma and convulsions, causing brain damage. Angong Niuhuang Pill (ANP), a traditional Chinese emergency medicine, has been employed in clinical practice for centuries, with well-documented antipyretic effects.
View Article and Find Full Text PDFBiomarkers
September 2025
ACTION Study Group, Pitié-Salpêtrière University Hospital, Paris, France.
Background: Identifying patients benefiting from implantable cardioverter defibrillators (ICD) especially when replacing one that has never served may be challenging.
Objectives: We assessed the association between plasma levels of mid-regional-pro-A-type-natriuretic peptide (ANP), Mid-regional-pro-adrenomedullin (ADM) and aldosterone and, appropriate Implantable Cardioverter Defibrillator (ICD)-therapy in patients with an ICD but no prior therapy.
Methods: A cohort of 331 consecutive patients with an ICD but no prior ICD-therapy was prospectively included in 2 centers and followed-up for a median of 7.
Anal Chem
September 2025
College of Chemistry and Chemical Engineering, Central South University, Changsha 410083, China.
Nanoplastics (NPs) and their aged counterparts (aNPs) pose growing environmental and health risks; however, their impact on cellular redox homeostasis remains poorly understood due to the difficulty in simultaneously assessing the amounts of cellular glutathione (GSH) and corresponding glutathione disulfide (GSSG) using traditional methods. Here, under NP and aNP postexposure, we introduce a photothermal convective capture SERS strategy to directly assess total glutathione (GSHt) and the GSH/GSSG ratio─critical biomarkers of oxidative stress. This method leverages laser-induced bubble formation on Au nanoisland (AuNIs) substrates to concentrate analytes via convective flow without the need for specific linkers or templates, enabling label-free, one-step detection with high sensitivity.
View Article and Find Full Text PDFFront Med (Lausanne)
August 2025
Emergency Department, Guangdong Province Hospital of Chinese Medicine, Guangzhou, China.
Background: Nocturia is a common and bothersome symptom in the elderly population, significantly impacting their quality of sleep and overall well-being. Heat-Sensitive moxibustion (HSM) is effective for elderly people with nocturia, but its efficacy has not been scientifically proven. This randomized controlled trial is designed to determine the efficacy and safety of HSM in the elderly with Nocturia.
View Article and Find Full Text PDF