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Objectives: To examine the clustering of overweight and obesity among adults within Indian households.
Study Design: Nationally representative cross-sectional study.
Methods: Data from the fifth round of the National Family Health Survey (NFHS-5, 2019-21) were analyzed to assess the prevalence of overweight and obesity among adults aged 15-54 years. The study encompassed 636,699 households and 761,885 individuals. Households were categorized based on the presence of overweight or obese members, and multilevel logistic regression was used to evaluate variations at the household, community, district, and regional levels.
Results: Nearly 20 % (95 % CI:19.1-19.5) of households in India had all adults classified as overweight, and 10 % (95 % CI:9.4-9.7) had all adults classified as obese. In states, such as Manipur, Kerala, Arunachal Pradesh, and Sikkim, over 30 % of households had all adults overweight. Additionally, in Tamil Nadu and Punjab, two out of every five households had all adults classified as obese. Among the households belonging to the richest wealth quintile, one in four had all members overweight, and 17.3 % (95 % CI:16.8-17.7) had all members classified as obese. The proportion of households with all obese members was nearly twice as high in urban areas (14.3-15.0 %) compared to their rural counterparts (7.1-7.4 %). Households belonging to Scheduled Tribes reported the lowest proportion of households with all members classified as obese, at only 4.2% (95% CI: 3.9-4.5), while households belonging to forward ('others') social group recorded the highest proportion, at 12.2% (95% CI: 11.8-12.5).
Conclusion: The clustering of overweight and obesity within households, particularly in southern states, among affluent populations, and in urban settings, underscores the importance of family-centered approaches to obesity prevention and intervention.
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http://dx.doi.org/10.1016/j.puhe.2025.105814 | DOI Listing |
PLoS One
September 2025
Department of Biological Sciences, University of Limerick, Limerick, Ireland.
This study investigates the interaction between circadian rhythms and lipid metabolism disruptions in the context of obesity. Obesity is known to interfere with daily rhythmicity, a crucial process for maintaining brain homeostasis. To better understand this relationship, we analyzed transcriptional data from mice fed with normal or high-fat diet, focusing on the mechanisms linking genes involved with those regulating circadian rhythms.
View Article and Find Full Text PDFPLoS One
September 2025
Department of Medicine, Faculty of Medicine, Universiti Malaya, Kuala Lumpur, Malaysia.
There is a lack of longitudinal data on type 2 diabetes (T2D) in low- and middle-income countries. We leveraged the electronic health records (EHR) system of a publicly funded academic institution to establish a retrospective cohort with longitudinal data to facilitate benchmarking, surveillance, and resource planning of a multi-ethnic T2D population in Malaysia. This cohort included 15,702 adults aged ≥ 18 years with T2D who received outpatient care (January 2002-December 2020) from Universiti Malaya Medical Centre (UMMC), Kuala Lumpur, Malaysia.
View Article and Find Full Text PDFJ Int Assoc Provid AIDS Care
September 2025
Department of Internal medicine, School of Medicine, College of Medicine and Health Sciences, University of Gondar, Gondar, Ethiopia.
BackgroundDolutegravir (DTG)-based antiretroviral treatment is now the recommended regimen because of its high efficacy and fewer adverse effects. Nonetheless, hyperglycemia as adverse effect of DTG was reported in few clinical observations.MethodsA case-control study was carried out among DTG-based antiretroviral therapy (ART) users during the study period.
View Article and Find Full Text PDFJAMA Netw Open
September 2025
Perelman School of Medicine, University of Pennsylvania, Philadelphia.
Importance: As obesity rates rise in the US, managing associated metabolic comorbidities presents a growing burden to the health care system. While bariatric surgery has shown promise in mitigating established metabolic conditions, no large studies have quantified the risk of developing major obesity-related comorbidities after bariatric surgery.
Objective: To identify common metabolic phenotypes for patients eligible for bariatric surgery and to estimate crude and adjusted incidence rates of additional metabolic comorbidities associated with bariatric surgery compared with weight management program (WMP) alone.
J Robot Surg
September 2025
Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, UT Health San Antonio, 7703 Floyd Curl Drive, 7836, San Antonio, TX, 78229-3900, USA.
To evaluate intraoperative ventilatory mechanics during robotic-assisted hysterectomy in obese women with endometrial cancer and introduce the concept of a physiologic "ceiling effect" in respiratory strain. We conducted a retrospective cohort study of 89 women with biopsy-confirmed endometrial cancer who underwent robotic-assisted total hysterectomy between 2011 and 2015. Intraoperative ventilatory parameters, including plateau airway pressure and static lung compliance, were recorded at five-minute intervals.
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