Category Ranking
98%
Total Visits
921
Avg Visit Duration
2 minutes
Citations
20
Article Abstract
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1164/rccm.202503-0615VP | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Verification of CT/MRI imaging protocol compliance for radiotherapy.
J Appl Clin Med Phys
September 2025
Icon Cancer Centre Toowoomba, Toowoomba, Queensland, Australia.
Introduction: The role of imaging in radiotherapy is becoming increasingly important. Verification of imaging parameters prior to treatment planning is essential for safe and effective clinical practice.
Methods: This study described the development and clinical implementation of ImageCompliance, an automated, GUI-based script designed to verify and enforce correct CT and MRI parameters during radiotherapy planning.
Transcriptional condensates enrich phosphorylated PRMT2 to stimulate H3R8me2a deposition and hypoxic response in glioblastoma.
Sci China Life Sci
September 2025
State Key Laboratory of Experimental Hematology, The Province and Ministry Co-sponsored Collaborative Innovation Center for Medical Epigenetics, Key Laboratory of Immune Microenvironment and Disease (Ministry of Education), Tianjin Medical University Cancer Institute and Hospital, Tianjin Key Labora
Histone arginine methylation by protein arginine methyltransferases (PRMTs) is crucial for transcriptional regulation and is implicated in cancers. Despite their therapeutic potential, some PRMTs present challenges as drug targets due to their context-dependent activities. Here, we demonstrate that hypoxia triggers the rapid condensation of PRMT2, which is essential for its histone H3R8 asymmetric dimethylation (H3R8me2a) activity.
View Article and Find Full Text PDFTemporal transcriptomics reveal crucial networks underlying jasmonate-mediated diurnal floret opening and closure in rice.
Sci China Life Sci
September 2025
State Key Laboratory of Plant Environmental Resilience, College of Life Sciences, Zhejiang University, Hangzhou, 310058, China.
Diurnal floret opening and closure (DFOC) is essential for rice reproductive development and hybrid breeding, yet transcriptional dynamics and underlying regulatory networks remain poorly characterized. Here, we conducted high-temporal-resolution transcriptomic analyses of lodicules to dissect DFOC regulatory networks in two japonica rice cultivars. Analysis of differentially expressed genes (DEGs) uncovered core genes shared by both cultivars, primarily associated with jasmonic acid (JA) signaling and cell wall remodeling.
View Article and Find Full Text PDFThe Key Role of Public Forests in Restoring Connectivity: an Application to Castilla y León Region, Spain.
Environ Manage
September 2025
TEMSUS Research Group, Catholic University of Ávila, Ávila, Spain.
Forests have been increasingly affected by natural disturbances and human activities. These impacts have caused habitat fragmentation and a loss of ecological connectivity. This study examines potential restoration pathways that reconnect the five largest forest cores in the Castilla y León region of Spain.
View Article and Find Full Text PDFX-Linked Hypophosphatemia: Role of Fibroblast Growth Factor 23 on Human Skeletal Muscle-Derived Cells.
Calcif Tissue Int
September 2025
FirmoLab, Fondazione F.I.R.M.O. Onlus and Stabilimento Chimico Farmaceutico Militare (SCFM), 50141, Florence, Italy.
X-linked hypophosphatemia (XLH) is a rare and progressive disease, due to inactivating mutations in the phosphate-regulating endopeptidase homolog X-linked (PHEX) gene. These pathogenic variants result in elevated circulating levels of fibroblast growth factor 23 (FGF23), responsible for the main clinical manifestations of XLH, such as hypophosphatemia, skeletal deformities, and mineralization defects. However, XLH also involves muscular disorders (muscle weakness, pain, reduced muscle density, peak strength, and power).
View Article and Find Full Text PDF