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This retrospective cohort study aimed to evaluate preoperative frailty in older adults undergoing brain tumor surgery using the laboratory-based frailty index (FI-LAB) and its association with clinical outcomes. Data were from electronic medical records of individuals aged ≥ 65 years who had brain tumor surgery between 2015 and 2022 at a general hospital in Seoul, South Korea. The FI-LAB included 26 preoperative laboratory tests and five vitality parameters. Of the 111 patients (mean age 75.4 years; 55% women; 63.1% had benign tumors), 35.1% exhibited moderate or high frailty. Moderate frailty was associated with higher hospital readmission rates (OR = 1.5; 95% CI, 1.01-1.82), and high frailty was linked to non-home discharge (OR = 2.1; 95% CI, 1.03-2.99). Assessing preoperative frailty with the FI-LAB may help identify risks of readmission or non-home discharge. Future studies with larger samples are needed to validate these findings. Nurses should integrate frailty assessment into practice to improve postoperative outcomes.
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http://dx.doi.org/10.1111/nhs.70168 | DOI Listing |
J Neurooncol
September 2025
Department of Neurosurgery, Paracelsus Medical University, Breslauer Straße 201, 90471, Nuremberg, Bavaria, Germany.
Purpose: Resection of glioblastomas infiltrating the motor cortex and corticospinal tract (CST) is often linked to increased perioperative morbidity. Navigated transcranial magnetic stimulation (nTMS) motor mapping has been advocated to increase patient safety in these cases. The additional impact of patient frailty on overall outcome after resection of cases with increased risk for postoperative motor deficits as identified with nTMS needs to be investigated.
View Article and Find Full Text PDFBackgrounds: Incidence of malignant disease in older patients has been increasing. These geriatric patients have more comorbidities and frailty than younger patients, necessitating different approaches in evaluation and treatment. Geriatric surgery studies in Japan have followed those conducted in the US.
View Article and Find Full Text PDFSemin Vasc Surg
September 2025
Division of Vascular and Endovascular Surgery, Brigham and Women's Hospital, 75 Francis Street, Boston, MA 02115; Center for Surgery and Public Health, Boston, MA; Harvard Medical School, Boston, MA. Electronic address:
The rate of end-stage kidney disease (ESKD) is steadily rising in the United States, and older adults (ie, 65 years and older) represent the fastest-growing segment in need of hemodialysis. This demographic shift presents unique challenges due to age-related comorbidities, frailty, and increased procedural risks. Despite these challenges, there is limited guidance for risk stratification and management of renal replacement therapy in older patients with ESKD.
View Article and Find Full Text PDFSemin Vasc Surg
September 2025
Division of Vascular and Endovascular Surgery, Department of Surgery, Stony Brook University Hospital, Health Sciences Tower, Stony Brook, NY, 11794. Electronic address:
Chronic mesenteric ischemia (CMI) is a rare, yet increasingly prevalent, condition, especially among older adults. Diagnosing CMI in older adults presents significant challenges. Along with the burden of comorbidities and the physiological changes associated with aging, timely intervention is often delayed, leading to poorer outcomes.
View Article and Find Full Text PDFPLoS One
September 2025
Department of Cardiac Surgery, Epworth Eastern Hospital, Box Hill, Victoria, Australia.
Introduction: This review was aimed at understanding the scope of evidence regarding outcomes and complications in nonagenarians (90-99 years of age) undergoing open cardiac surgery.
Methods: The review was conducted in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) Extension for Scoping Review Protocol guidelines. A search of three databases, MEDLINE, EMBASE, and the Cochrane Central Register of Controlled Trials, identified articles pertaining to nonagenarians undergoing various open cardiac surgical procedures.