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http://dx.doi.org/10.1016/j.athoracsur.2025.06.006 | DOI Listing |
J Clin Med
August 2025
Pulmonology Department, CUF Tejo Hospital, 1998-018 Lisbon, Portugal.
Obstructive sleep apnea (OSA) is a highly prevalent and underdiagnosed sleep disorder with significant cardiovascular implications, namely in atrial fibrillation (AF) patients. Despite its clinical relevance, OSA prevalence among AF patients and the diagnostic strategies used remain heterogeneous across studies, complicating screening, and treatment pathways. Our aim was to synthesize recent evidence on OSA prevalence in AF populations and to critically evaluate the diagnostic methods and screening strategies employed in clinical studies, by conducting a systematic review using PubMed and Google Scholar to identify original clinical studies published between January-2019 and December-2024.
View Article and Find Full Text PDFNPJ Clim Atmos Sci
August 2025
Atmospheric, Oceanic and Planetary Physics, University of Oxford, Oxford, UK.
Evidence has emerged of a discrepancy in tropical Pacific sea surface temperature (SST) trends over the satellite era, where most coupled climate models struggle to simulate the observed La Niña-like SST trends. Here we highlight wider implications of the tropical Pacific SST trend discrepancy for global circulation trends during boreal winter, using two complementary methods to constrain coupled model SST trends: conditioning near-term climate prediction (hindcast) simulations, and pacemaking coupled climate simulations. The robust circulation trend response to constraining the tropical Pacific SST trend resembles the interannual La Niña response.
View Article and Find Full Text PDFJ Pharm Bioallied Sci
July 2025
Department of Physiology, Government Erode Medical College, Perundurai, Erode, Tamil Nadu, India.
Background: Drug-induced QTc prolongation is a significant concern in critically ill patients, increasing the risk of life-threatening arrhythmias. This prospective observational study evaluates the association between QTc prolongation, serum potassium and magnesium levels, and clinical outcomes in adult medical intensive care unit (ICU) patients.
Methodology: The study included 116 adult ICU patients prescribed QTc-prolonging drugs, excluding those with atrial fibrillation, pacemakers, or early transfers.
Neuromodulation
August 2025
Auckland Bioengineering Institute, University of Auckland, Auckland, New Zealand.
Purpose: Compromised electrical and mechanical activity in the gastrointestinal tract is associated with several motility disorders. Conventional treatment fails in a significant proportion of the patient population, and pacing is a promising alternative therapy. However, the correlation between slow waves and contractions during pacing remains unexplored.
View Article and Find Full Text PDFJACC Case Rep
August 2025
Division of Cardiology, MedStar Heart and Vascular Institute, MedStar Washington Hospital Center, Washington, DC, USA. Electronic address:
Background: Iatrogenic ventricular septal defects (VSDs) are rare but important complications of transcatheter aortic valve replacement (TAVR). In patients who develop conduction abnormalities post-TAVR, the presence of a VSD can complicate pacing strategies.
Case Summary: We report 2 cases of perimembranous VSDs after TAVR, both complicated by conduction disease and managed with left bundle branch pacing (LBBP).