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Article Abstract
Objective: To assess the safety and effectiveness of combining indocyanine green videoangiography with FLOW800 and multimodal fusion neuro-navigation in brain arteriovenous malformation (AVM) microsurgical resection.
Methods: From January 1, 2019 to December 31, 2022, 90 consecutive patients at The First Affiliated Hospital of Soochow University diagnosed with AVMs were included. Patients were divided into a combined treatment group and a noncombined treatment group based on the treatment received. Clinical data including baseline characteristics, image findings, modified Rankin Score, and preoperation and postoperation hemoglobin (Hb)/hematocrit (HCT) levels were reviewed and collected for statistical analysis.
Results: Compared with the noncombined treatment group, the combined treatment group demonstrated a smaller postoperative decline in Hb and HCT levels after operation and a higher proportion of patients with no disability at discharge and at the 6-month follow-up. Additionally, the combined treatment group had lower rates of reoperation and postoperative complications. Compared with the noncombined treatment group, the combined treatment group demonstrated a smaller postoperative decline in Hb and HCT levels and a higher proportion of patients with no disability at discharge and at the 6-month follow-up. Additionally, the combined treatment group had lower rates of reoperation and postoperative complications.
Conclusions: The combined utilization of intraoperative indocyanine green videoangiography with FLOW800 and multimodal fusion neuro-navigation appears to reduce intraoperative blood loss and enhance functional outcomes in AVM microsurgery, thereby improving both the safety and efficacy of the procedure.
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| http://dx.doi.org/10.1016/j.wneu.2025.124193 | DOI Listing |
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