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Objective: Femoral access site complications influence short term survival and outcomes in patients undergoing endovascular procedures. While ultrasound guided puncture is a reliable method to reduce such complications, ultrasound guidance is rarely used for closure device deployment.
Data Sources: Web of Science, PubMed, and the Cochrane Library.
Review Methods: A systematic literature search was conducted to assess the safety and efficacy of ultrasound guided vascular closure device deployment compared with vascular closure device deployment without ultrasound guidance, referred to as conventional closure. All studies reporting on ultrasound guided closure in transfemoral arterial interventions were eligible, and those directly comparing ultrasound guided with conventional closure were included in the meta-analysis.
Results: Overall, 2 738 patients receiving ultrasound guided closure were included: 1 025 for introducer sheaths measuring 12 F or larger and 1 713 for introducer sheaths smaller than 12 F. The incidence of access complications was 5.7% (range 0.8 - 21.6%) for large sheath procedures and 2.6% (range 0.9 - 4.7%) for small sheath procedures. The meta-analysis, which included 2 339 patients who received ultrasound guided closure and 1 175 who underwent conventional closure, showed that ultrasound guided closure was associated with reduced access site complications compared with conventional closure (odds ratio [OR] 0.49, 95% confidence interval [CI] 0.37 - 0.65; p < .001). This was consistently seen both for small sheath (OR 0.45, 95% CI 0.28 - 0.75; p = .002) and large sheath procedures (OR 0.50, 95% CI 0.37 - 0.71; p < .001), but with a low certainty of evidence in the Grading of Recommendations Assessment, Development, and Evaluation (GRADE) analysis.
Conclusion: Ultrasound guided vessel closure of the femoral artery appeared to be associated with a lower rate of overall access site complications compared with conventional closure techniques. Therefore, ultrasound guided closure might offer the potential to increase procedural and patient safety in percutaneous arterial access.
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http://dx.doi.org/10.1016/j.ejvs.2025.06.023 | DOI Listing |
J Eval Clin Pract
September 2025
Department of Orthopedics and Traumatology, Medical Faculty, University of Health Sciences, Antalya, Turkey.
Aims And Objective: The field of medical statistics has experienced significant advancements driven by integrating innovative statistical methodologies. This study aims to conduct a comprehensive analysis to explore current trends, influential research areas, and future directions in medical statistics.
Methods: This paper maps the evolution of statistical methods used in medical research based on 4,919 relevant publications retrieved from the Web of Science.
Curr Opin Endocrinol Diabetes Obes
October 2025
Department of Surgery, American Mission Hospital, Manama, Bahrain.
Purpose Of Review: To review the current medical evidence in the diagnosis and management of thyroid nodules.
Recent Findings: The widespread use of imaging modalities in recent years has led to frequent discovery of incidental thyroid nodules. These nodules are mostly benign (over 90%), hence precise insight in evaluating nodules of concern and following up other nodules is important to avoid unnecessary surgeries and its complications.
Foot Ankle Int
September 2025
Department of Orthopaedic Surgery, St. Luke's University Health Network, Bethlehem, PA, USA.
Background: In response to the opioid epidemic, many surgical specialties have adopted nonopioid pain management strategies. Ultrasound (US)-guided peripheral nerve blocks (PNBs) are effective in reducing pain and opioid consumption postsurgery. Liposomal bupivacaine (LB), shown effective in shoulder surgery, was approved in November 2023 for use in US-guided lower extremity blocks.
View Article and Find Full Text PDFCancer Rep (Hoboken)
September 2025
Division of Gastroenterology, Department of Internal Medicine, Asahikawa Medical University, Asahikawa, Japan.
Background: Cancer of unknown primary (CUP) is a challenging malignancy characterized by metastatic tumors with an unidentified primary site, even after extensive pathological and radiographic evaluation. Recent advancements in gene expression profiling and comprehensive genomic profiling (CGP) using next-generation sequencing (NGS) have enabled the identification of potential tissue origins, thereby facilitating personalized treatment strategies. Although most cases of CUP present as adenocarcinomas or poorly differentiated tumors, the treatment remains largely empirical, with limited success from molecularly tailored therapies.
View Article and Find Full Text PDFKorean J Pain
September 2025
Department of Nursing, Chungnam National University College of Nursing, Daejeon, Korea.
Background: Ultrasound-guided abdominal wall blocks are increasingly used to enhance postoperative analgesia in laparoscopic nephrectomy. Among these, the transversus abdominis plane (TAP) block and the quadratus lumborum (QL) block have emerged as promising techniques. However, no comprehensive review has yet compared the analgesic efficacy of these two regional approaches.
View Article and Find Full Text PDF