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BackgroundSpinocerebellar ataxia (SCA) is a neurodegenerative disease causing weakness and balance disorders that affected quality of life. Whole body vibration (WBV) had been reported to facilitate neuromuscular contraction in healthy people and athletes.ObjectiveThe purpose of this study was to investigate whether four weeks of WBV training can enhance central and peripheral muscle strength and balance performances in patients with SCA.MethodsThirteen individuals with diagnosed SCA were randomly assigned into WBV and control groups. Subjects in the training group received four weeks of WBV training at semi-squatting position for 3 sessions per week; whereas subjects in the control group performed semi-squatting position for the same duration. The maximum voluntary contraction (MVC), voluntary activation level (VA), twitch force, Berg balance scale (BBS), and one-leg standing time were evaluated before and after training. All subjects in the training group could tolerate the WBV training.ResultsThe MVC of soleus, the VA of plantar flexors and knee extensors, the score of BBS (p < 0.05) and one-leg standing time improved (p < .05) only in the training group.ConclusionsWBV training is a feasible rehabilitation strategy which can improve general and central origin force and balance performance in individuals with SCA.
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http://dx.doi.org/10.1177/10538135251325477 | DOI Listing |
ACS Omega
September 2025
Laboratório de Biotecnologia Farmacêutica (pbiotech), Faculdade de Farmácia, Universidade Federal do Rio de Janeiro, Rio de Janeiro, RJ 21941-902, Brazil.
The crystallographic B-factor (Bf), also known as the Debye-Waller factor (DWF) or temperature factor, relates to the mean-square displacement of the atoms (X). X may be composed of individual contributions from lattice disorder (LT), static conformational heterogeneity (H) throughout the lattice, rigid body vibration (RB), local conformational vibration (V), and zero-point atomic fluctuation (A). The Bf has been widely employed as a surrogate measure of local protein flexibility, although such relation has not been confirmed.
View Article and Find Full Text PDFPhysiol Behav
September 2025
Institute of Physical Education, Health and Leisure Studies, National Cheng Kung University, Taiwan; Department of Psychology, National Cheng Kung University, Taiwan. Electronic address:
This study investigated the effects of moderate-intensity aerobic exercise (MIAE) and MIAE combined with isometric resistance exercise on a whole-body vibration (WBV) platform (MIAE+WBV) compared with the effects of no exercise (NEI) on neurocognitive and molecular indices in 71 sedentary, healthy postmenopausal women. Participants were randomly assigned to MIAE (n = 23), MIAE+WBV (n = 23), and NEI (n = 25) groups. Neurocognitive measures, including accuracy rate (AR), reaction time (RT), and electroencephalogram-based event-related potentials (P2, N2, and P3 components) during the Stroop task, in addition to serum levels of insulin-like growth factor 1 (IGF-1), norepinephrine (NE), osteocalcin (OC), carboxylated OC (cOC), and uncarboxylated OC (ucOC), were evaluated before and after the intervention.
View Article and Find Full Text PDFZhonghua Lao Dong Wei Sheng Zhi Ye Bing Za Zhi
August 2025
School of Public Health, North China University of Science and Technology, Tangshan 063210, China Hebei Coordinated Innovation Center of Occupational Health and Safety, Tangshan 063210, China.
To investigate the occurrence of work-related musculoskeletal disorders (WMSDs) among underground coal mine workers, identify the risk factors for WMSDs, and provide a scientific evidence for the prevention and treatment of WMSDs. In March 2024, through cluster sampling, the on-the-job workers who underwent questionnaire surveys and health examinations at a certain coal mine from July to August 2018 were selected as the research subjects. Basic information of employees, ergonomics-related characteristics, and the occurrence status of WMSDs in each part were collected, and multivariate logistic regression was used for analysis.
View Article and Find Full Text PDFProc Inst Mech Eng H
September 2025
School of Mechanical Engineering and Automation, Northeastern University, Shenyang, China.
The effects of vehicle-induced whole-body vibration on human body have received widespread attention, and investigations have found that vibrations would cause lumbar disorders of occupational drivers. Some investigations have revealed the harmful effects of vibrations on human body, but the studies about the effect of vibration applied to different body regions on lumbar spine are limited. In this study, a whole-body finite element model was used to predict the biomechanical response of lumbar spine under vibrations applied to the back of thoracic and lumbar regions, and the bottom of buttock regions, respectively.
View Article and Find Full Text PDFPediatr Phys Ther
September 2025
Hillsboro, Oregon (Dr Quinn); Oregon Health & Science University, Portland, Oregon (Dr Sloane).
Purpose: This case report describes the combined use of whole-body vibration (WBV), serial casting (SC), and physical therapy (PT) for a child with hemiplegic cerebral palsy (HCP).
Summary Of Key Points: A 3-year 10-month-old male with HCP was followed for 10 months. Treatment included 9 weeks of SC due to ankle plantarflexion contracture, hypertonicity, poor orthotic tolerance, and gait limitations.