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Purpose: To evaluate the impact of direct in-scope suction (DISS) on intrarenal pressure (IRP) using two different-sized flexible ureteroscopes (7.5Fr and 9.2Fr) in combination with various sized ureteral access sheaths (UAS).
Material And Methods: In this ex-vivo experimental study using a porcine kidney model, pressure measurements were conducted using two venous catheters placed in the upper and lower calyces. We tested 7.5Fr (3.6Fr working channel) and 9.2Fr (5.1Fr working channel) flexible ureteroscopes with DISS systems with 9.5/11.5Fr, 11/13Fr, and 12/14Fr UASs. Measurements were taken at irrigation pressures of 40-100 mmHg, evaluating the effects of suction modes (none vs active).
Results: The 9.2Fr scope generated higher baseline pressures (maximum 23 mmHg) compared to the 7.5Fr scope (maximum 7 mmHg) at 100 mmHg irrigation. One second of active achieved significant pressure reduction from 20-23mmHG to 3 mmHg for 9.2Fr DISS scope with 100 mmHg pressure setting and to 0 mmHg in all other settings with both scopes. The 9.2Fr scope demonstrated faster pressure recovery (8-14 s) compared to the 7.5Fr scope (10-32 s).
Conclusions: Higher intrarenal pressures can be expected with the 9.2Fr scope compared to the 7.5Fr scope, regardless of irrigation power and UAS size. Rapid and significant reduction of pressure occurs only after 1 s of suction activation. This effect is more pronounced with the 9.2Fr ureteroscope that is supplied with a wider working channel measuring 5.1Fr. The 9.2Fr scope requires shorter time to regain initial pressure compared to the 7.5Fr scope (3.6Fr working channel).
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http://dx.doi.org/10.1007/s00345-025-05744-9 | DOI Listing |
Med Eng Phys
October 2025
College of Basic Medical Science, Shanxi University of Chinese Medicine, Jinzhong, 030619, Shanxi, China.
Pulse diagnosis holds a pivotal role in traditional Chinese medicine (TCM) diagnostics, with pulse characteristics serving as one of the critical bases for its assessment. Accurate classification of these pulse pattern is paramount for the objectification of TCM. This study proposes an enhanced SMOTE approach to achieve data augmentation, followed by multi-domain feature extraction.
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September 2025
College of Pharmacy, Shandong University of Traditional Chinese Medicine, Jinan, 250355, China; Key Laboratory of Traditional Chinese Medicine Classical Theory, Ministry of Education, Shandong University of Traditional Chinese Medicine, Jinan, 250355, China. Electronic address:
The thermosensitive transient receptor potential (Thermo-TRP) channel proteins comprise TRPA1, TRPV1-V4, and TRPM8. TRP channels are mainly situated on cellular surfaces and react to a range of external factors, including heat, cold, acidity, osmotic pressure, chemical signals, and flavors, as well as intracellular signals such as Ca, Na, and cytokines. The thermo-TRP channels are associated with many physiological signal pathways, with their distinct molecular structure making them promising drug targets for respiratory diseases.
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September 2025
electrical engineering department, Indian Institute of Technology Roorkee, Research wing, electrical department, Roorkee, uttrakhand, 247664, INDIA.
Imagined speech classification involves decoding brain signals to recognize verbalized thoughts or intentions without actual speech production. This technology has significant implications for individuals with speech impairments, offering a means to communicate through neural signals. The prime objective of this work is to propose an innovative machine learning (ML) based classification methodology that combines electroencephalogram (EEG) data augmentation using a sliding window technique with statistical feature extraction from the amplitude and phase spectrum of frequency domain EEG segments.
View Article and Find Full Text PDFJ Colloid Interface Sci
September 2025
College of Chemistry and Molecular Engineering, Qingdao University of Science and Technology, Qingdao 266042, PR China. Electronic address:
Transition metal fluorides because of the high electronegativity of fluorine may enhance the local electron density of the metal sites and promote water molecule dissociation and charge transfer. However, enhancing the intrinsic activity of fluorides to improve material stability remains a challenge. Herein, we develop an innovative four-step synthetic strategy (electrochemical deposition → co-precipitation → ligand exchange → in situ fluorination) to engineer three-dimensional porous Fe-doped CoF nanocubes vertically anchored on MXene (Fe-CoF/MXene/NF).
View Article and Find Full Text PDFNeural Netw
September 2025
Dept. of CSE, Konkuk University, Seoul, 05029, Republic of Korea. Electronic address:
Neural network compression problems have been extensively studied to overcome the limitations of compute-intensive deep learning models. Most of the state-of-the-art solutions in this context are based on network pruning that identify and remove unimportant weights, filters or channels. However, existing methods often lack actual speedup or require complex pruning criteria and additional training (fine-tuning) overhead.
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