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As a brain-inspired optical computing architectures, diffractive optical neural networks (DONN) harness light's wave nature for high-speed, energy efficient and parallel information processing, enabling applications such as image classification and wavefront shaping. However, conventional spatially encoded DONNs struggle with robustness in complex and unpredictable environments, where occlusions and distortions degrade processing accuracy. To address these challenges, we propose a robust all-optical feature extraction framework based on orbital angular momentum (OAM). This approach converts optical information into target OAM modes using a diffractive processing framework trained via deep learning, enabling stable and efficient information representation in the OAM domain. Unlike conventional DONNs, our method maintains high performance across diverse and irregular occlusions without requiring network retraining. This self-adaptive occlusion immune operates with zero additional training samples, effectively enhancing optical computing tasks under dynamic and uncertain conditions. By fully utilizing the helical wavefront and orthogonality of OAM, our approach improves the robustness and scalability of DONNs, demonstrating superior performance in challenging optical environments. Our work paves the way for next-generation optical computing systems that can operate reliably in unpredictable and occlusion-rich environment, unlocking what we believe to be new possibilities for robust, real-time processing in a variety of applications.
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http://dx.doi.org/10.1364/OE.564283 | DOI Listing |
Phys Rev Lett
August 2025
Universität Innsbruck, Institut für Experimentalphysik, Technikerstrasse 25, 6020 Innsbruck, Austria.
Establishing networks of quantum processors offers a path to scalable quantum computing and applications in communication and sensing. This requires first developing efficient interfaces between photons and multiqubit registers. In this Letter, we show how to entangle each individual matter qubit in a register of ten to a separate traveling photon.
View Article and Find Full Text PDFSci Adv
September 2025
Electrical and Computer Engineering Department, University of Washington, Seattle, WA 98105, USA.
Optomechanical and electro-optomechanical systems have emerged as one of the most promising approaches for quantum microwave-to-optical transduction to interconnect distributed quantum modalities for scaling the quantum systems. These systems use suspended structures to increase mode overlap and mitigate loss to achieve high efficiency. However, the suspended design's poor heat dissipation under strong drive limits the ultimate efficiency.
View Article and Find Full Text PDFSci Transl Med
September 2025
Burn Injury Research Unit, School of Biomedical Sciences, University of Western Australia, Perth, Western Australia 6009, Australia.
Skin scars remain a substantial clinical challenge because of their impact on appearance and psychological well-being. Lysyl oxidases catalyze collagen cross-linking, a key factor in scar development. Here, we report a randomized, double-blind, placebo-controlled phase 1 study to assess the safety and tolerability of PXS-6302, a topical pan-lysyl oxidase inhibitor, in treating mature scars (ACTRN12621001545853).
View Article and Find Full Text PDFPLoS One
September 2025
Computational Chemistry Laboratory, Chemistry Department, Faculty of Science, Minia University, Minia, Egypt.
Polar protic and aprotic solvents can effectively simulate the maturation of breast carcinoma cells. Herein, the influence of polar protic solvents (water and ethanol) and aprotic solvents (acetone and DMSO) on the properties of 3-(dimethylaminomethyl)-5-nitroindole (DAMNI) was investigated using density functional theory (DFT) computations. Thermodynamic parameters retrieved from the vibrational analysis indicated that the DAMNI's entropy, heat capacity, and enthalpy increased with rising temperature.
View Article and Find Full Text PDFPhys Rev Lett
August 2025
RIKEN, Center for Quantum Computing, Wakoshi, Saitama 351-0198, Japan.
Disorder and non-Hermitian effects together can upend how waves localize. In a 1D disordered chain, the non-Hermitian skin effect (NHSE) can induce Anderson delocalization, defying the usual rule that disorder in low dimensions always localizes states. While weak disorder leaves the NHSE intact, strong disorder restores Anderson localization.
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