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Aim: The aim of this study was to determine how Low-level laser therapy (LLLT) post- Scaling and root planning (SRP) affected the inflammatory periodontal tissue caused by chronic periodontitis.
Methodology: The study involved 56 sites in 28 patients with almost bilaterally symmetrical moderate pocket depths. The sites were split into two groups at random. SRP was administered alone to Group I, while SRP with LLLT were administered to Group II. In addition to recording the clinical parameters [plaque index (PI), sulcus bleeding index (SBI), and probing pocket depth (PPD)], GCF sample was taken at baseline, 3 to 4 weeks, and 6 to 7 weeks from baseline. The visual analogue scale (VAS) was scored for both groups on the final day of LLLT, which was 7 days following SRP. All GCF samples were then sent for TGF-β1 and PGE2 biochemical analysis.
Results: This study demonstrated a significant reduction in PI, SBI, PPD, VAS score, PGE2 and TGF- β1 level in GCF in group I after SRP. Similarly in group II, which received LLLT with SRP, showed a significant decrease in all clinical and biochemical parameters. Intergroup comparison showed no significant difference in PI, SBI, TGF-β1 levels in the GCF. However, there was a significant difference in PPD, VAS score, and PGE2 level results.
Conclusion: Our study concluded that LLLT may be effective in reducing inflammation when used as an adjunct to SRP.
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http://dx.doi.org/10.4103/jpbs.jpbs_1930_24 | DOI Listing |
Pol Merkur Lekarski
September 2025
Kharkiv Clinical Hospital on Railway Transport No. 1 ≪Health Care Center≫ of Joint-Stock Company «Ukrainian Railways», Kharkiv, Ukraine.
Objective: Aim: The purpose was to identify the morphological features of the great saphenous vein in patients with chronic venous disease of the lower extremities undergoing treatment with endovenous high-frequency electric welding in automatic mode, endovenous laser ablation, and ultrasound-guided microfoam sclerotherapy.
Patients And Methods: Materials and Methods: The material for the comprehensive morphological study consisted of fragments of the great saphenous vein obtained from 32 patients with chronic venous disease of the lower extremities. The material was divided into three groups according to the endovenous treatment techniques applied.
Photobiomodul Photomed Laser Surg
September 2025
Department of Oral and Maxillofacial Diagnostic Sciences, Dental College and Hospital, Taibah University, Medina, Saudi Arabia.
Photobiomodulation (PBM) therapy involves the use of low-dose, nonionizing light to reduce pain and inflammation, promote wound healing, and enhance tissue regeneration. PBM-based therapy of various dental conditions is associated with improved treatment outcomes. This study aims to critically review the literature to highlight the underlying molecular biological mechanisms and clinical applications of PBM in modern dental practice.
View Article and Find Full Text PDFLasers Med Sci
September 2025
Laser Research Center of Dentistry, Dentistry Research Institute, Tehran University of Medical Sciences, Tehran, Iran.
Microbial contamination of absorbable collagen membranes used in guided bone regeneration (GBR) may compromise healing outcomes. This study aimed to investigate whether the minimum inhibitory concentration (MIC) of hydrogen peroxide (HO) can improve the antibacterial effect of indocyanine green (ICG)-mediated antimicrobial photodynamic therapy (PDT) on absorbable collagen membranes while reducing the need for high HO concentrations. A laboratory-based model was developed using Streptococcus sanguinis and Staphylococcus aureus.
View Article and Find Full Text PDFSupport Care Cancer
September 2025
Department of Oral Pathology, School of Dentistry, Universidade Federal do Rio Grande do Sul, Porto Alegre, RS, Brazil.
Purpose: To compare the efficacy of intraoral (IOPBM) and extraoral photobiomodulation (EOPBM) protocols for the prevention and treatment of oral mucositis (OM) in patients with oral or oropharyngeal squamous cell carcinoma (SCC) to submitted radiotherapy (RT).
Methods: This randomized, blinded, multicenter clinical trial enrolled 58 patients with oral or oropharyngeal SCC, who were allocated into two groups matched by treatment type, clinical stage, and RT modality. Group I (IOPBM) received intraoral photobiomodulation (PBM) with a continuous InGaAlP diode laser (660 nm, 100 mW, 0.
J Vet Intern Med
September 2025
Schwarzman Animal Medical Center, New York, New York, USA.
Background: There are limited studies on cystoscopic-guided laser ablation for treating ectopic ureters in male dogs. Further investigation is needed to assess its safety and efficacy.
Hypothesis/objective: Retrospectively describe long-term outcomes in male dogs treated using cystoscopic-guided laser ablation of ectopic ureters (CLA-EU).