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http://dx.doi.org/10.1111/liv.70176 | DOI Listing |
J Agric Food Chem
September 2025
College of Food Science and Engineering, Ocean University of China, Qingdao 266404, PR China.
Sulfated fucan has attracted growing attention due to its diverse biological properties. Endo-1,3-fucanases are valuable tools for the degradation of sulfated fucan. This study characterized an endo-1,3-fucanase Fun174Sb from the GH174 family, utilizing a combination of protein crystallography, mutagenesis, computational biology, and nuclear magnetic resonance techniques.
View Article and Find Full Text PDFFood Res Int
November 2025
State Key Laboratory of Food Science and Resources, Jiangnan University, Wuxi 214122, China; School of Food Science and Technology, Jiangnan University, Wuxi 214122, China; International Joint Laboratory on Food Safety, Jiangnan University, Wuxi 214122, China. Electronic address:
Food allergies pose a significant global health challenge, underscoring the need for effective detection and suppression methods. Conventional detection methods, such as ELISA and PCR, are often limited by challenges related to sensitivity and specificity, particularly when applied to complex food matrices. This review presents an overview of recent advancements in aptamer-based technologies, which present a promising approach for food allergen detection due to their high specificity and affinity for target molecules.
View Article and Find Full Text PDFInorg Chem
September 2025
Institutes of Physical Science and Information Technology, Key Laboratory of Structure and Functional Regulation of Hybrid Materials (Anhui University), Ministry of Education, Hefei 230601, P. R. China.
Precisely structured nanoclusters provide ideal platforms for elucidating structural evolution and structure-activity relationships. However, mechanistic understanding of dynamic core-shell rearrangements has long been impeded by the elusive nature of intermediates during transformation processes. Here, we show that ligand engineering-driven asymmetric thiolate exchange enables atomic-level visualization of structural evolution, thereby overcoming the long-standing challenge of intermediate capture.
View Article and Find Full Text PDFMagn Reson Lett
May 2025
National Center for Magnetic Resonance in Wuhan, State Key Laboratory of Magnetic Resonance and Atomic and Molecular Physics, Wuhan Institute of Physics and Mathematics, Innovation Academy for Precision Measurement Science and Technology, Chinese Academy of Sciences, Wuhan, 430071, China.
Organic structure directing agents (OSDAs), such as tetrapropylammonium (TPA) cations, serve as crucial templates for the formation of zeolite frameworks. These organic molecules interact with inorganic species, guiding the assembly of the zeolite structure. In this study, we investigate the complex interplay between boron species and TPA cations during the crystallization of [B, Al]-ZSM-5 zeolites.
View Article and Find Full Text PDFCurr Gene Ther
August 2025
State Key Laboratory of Vascular Homeostasis and Remodeling, Department of Neurosurgery, Peking University Third Hospital, Peking University, Beijing 100191, China.
Cerebral Cavernous Malformations (CCMs) are vascular anomalies in the central nervous system that arise from both genetic and non-genetic factors, and can cause hemorrhage, seizures, and neurological deficits. Approximately 80% of CCMs are sporadic, while 20% are Familial (FCCMs), an autosomal dominant, monogenic disorder characterized by multiple lesions and severe clinical manifestations. Over the past three decades, linkage analyses have identified KRIT1/CCM1, MGC4607/CCM2, and PDCD10/CCM3 as major pathogenic genes in FCCMs.
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