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The Immunization and Vaccines-related Implementation Research Advisory Committee (IVIR-AC) serves as the World Health Organization's (WHO) key advisory body for independently reviewing research that assesses the impact and value of vaccines, particularly using transmission and economic modeling analyses. During its first semi-annual meeting of 2025, held on 17-21 February and complemented by ad hoc sessions on 5 February, 11 April and 14 April, IVIR-AC provided feedback and recommendations across seven key sessions. This report summarizes the discussions and outcomes of the meeting. Topics covered included immunization research priorities in the WHO Eastern Mediterranean region, multi-model comparisons of typhoid conjugate vaccine schedules, a malaria intervention multi-model comparison, a full value assessment of invasive non-typhoidal Salmonella (iNTS) vaccination, an evaluation of improved influenza vaccines, vaccine impact modeling under the Immunization Agenda 2030 (IA2030) framework, and combination vaccines value assessment.
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http://dx.doi.org/10.1016/j.vaccine.2025.127384 | DOI Listing |
JMIR Hum Factors
September 2025
Seidenberg School of Computer Science and Information Systems, Pace University, New York City, NY, United States.
Background: As information and communication technologies and artificial intelligence (AI) become deeply integrated into daily life, the focus on users' digital well-being has grown across academic and industrial fields. However, fragmented perspectives and approaches to digital well-being in AI-powered systems hinder a holistic understanding, leaving researchers and practitioners struggling to design truly human-centered AI systems.
Objective: This paper aims to address the fragmentation by synthesizing diverse perspectives and approaches to digital well-being through a systematic literature review.
JMIR Hum Factors
September 2025
Department of Community Health Systems, University of California, San Francisco, School of Nursing, San Francisco, CA, United States.
Background: The COVID-19 pandemic forced the world to quarantine to slow the rate of transmission, causing communities to transition into virtual spaces. Asian American and Pacific Islander communities faced the additional challenge of discrimination that stemmed from racist and xenophobic rhetoric in the media. Limited data exist on technology use among Asian American and Pacific Islander adults during the height of the COVID-19 shelter-in-place period and its effect on their physical and mental health.
View Article and Find Full Text PDFJAMA Cardiol
September 2025
Department of Medicine, Cardiovascular Medicine, Stanford University, Stanford, California.
Importance: Consumer wearable technologies have wide applications, including some that have US Food and Drug Administration clearance for health-related notifications. While wearable technologies may have premarket testing, validation, and safety evaluation as part of a regulatory authorization process, information on their postmarket use remains limited. The Stanford Center for Digital Health organized 2 pan-stakeholder think tank meetings to develop an organizing concept for empirical research on the postmarket evaluation of consumer-facing wearables.
View Article and Find Full Text PDFJAMA Netw Open
September 2025
School of Nursing, Capital Medical University, Beijing, China.
Importance: The efficacy of home end-of-life care in enhancing the quality of life for terminally ill patients and families has been well documented. While previous studies have explored perspectives on quality home palliative care and end-of-life care in several countries, limited knowledge exists regarding its specific components in the Chinese context.
Objective: To explore the core elements that constitute quality home end-of-life care in China.
Cereb Cortex
August 2025
Section of Brain Function Information, National Institute for Physiological Sciences, 38 Nishigonaka, Myodaiji, Okazaki, Aichi 444-8585, Japan.
This study aimed to identify brain activity modulations associated with different types of visual tracking using advanced functional magnetic resonance imaging techniques developed by the Human Connectome Project (HCP) consortium. Magnetic resonance imaging data were collected from 27 healthy volunteers using a 3-T scanner. During a single run, participants either fixated on a stationary visual target (fixation block) or tracked a smoothly moving or jumping target (smooth or saccadic tracking blocks), alternating across blocks.
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