Mathematical proof of the Fisher-Escolà statistical distribution in quantum consciousness modeling.

Quantum theories have long sought to explain conscious experience, yet their biggest challenge is not conceptual but methodological. A critical gap remains: the lack of statistical tools capable of empirically testing these theories against objective reality. This study introduces and formalizes the of Fisher-Escolà distribution, the first statistical model to integrate quantum and classical probabilities, enabling robust inferential analysis in neuroscience and consciousness studies. We examined 150 density matrices of entangled states in a 10-qubit quantum system using 's quantum supercomputers. Through , we mathematically confirmed that ∼ (, , loc, scale). As a key contribution, a novel analytical solution to the (QFI) integral was derived, improving decoherence stability. Additionally, 10⁵ simulations allowed us to establish critical thresholds for α = 0.05, 0.01, 0.001, and 0.0001, while assessing Type I and II error rates. Type I errors appeared in 2-5 % of right-tailed tests at α = 0.05 but approached zero as α decreased. Type II errors occurred in left-tailed tests (1-4 % at α = 0.05) but also diminished with stricter significance levels. In two-tailed tests, both error types remained below 3 %, highlighting the distribution's robustness. The of Fisher-Escolà distribution pioneers a statistical framework for modeling quantum-classical interactions in consciousness research. It enables hypothesis testing and predicting subjective experiences, with applications in neuroscience and computational automation. Supported by mathematical proofs and empirical validation, this model advances the integration of quantum probability into neuroscience.