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Herein, we report a case of focal periphyseal edema in a 12-year-old female tennis player. The onset of chronic knee pain in adolescents has differential diagnoses, including fatigue fracture, epiphysis (Osgood-Schlatter disease), growth plate injury, Brodie abscess, patella-femoral malalignment, neoplasia, and meniscus tears. In this case, magnetic resonance imaging revealed focal bone marrow edema around the center of the epiphyseal plate of the distal femur. Three months later, the patient experienced residual knee pain, with no improvement visible on re-imaging. However, symptoms of the patient resolved, and the bone marrow edema disappeared 10 months after the initial visit. This is the first report to follow both clinical symptoms and the concurrent magnetic resonance imaging findings during the period from onset to cure in a patient with focal periphyseal edema of the knee.
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http://dx.doi.org/10.1016/j.radcr.2025.04.020 | DOI Listing |
Cureus
July 2025
Sports Medicine, Ascension Providence Hospital, Southfield, USA.
Focal periphyseal edema (FOPE) is a normal physiological finding that is often incidentally discovered on MRI of the knee. FOPE zones are areas of periphyseal edema typically observed near the time of physeal closure. This common physiologic phenomenon is related to changes in the distribution of forces around the physis as it closes during adolescence, occurring more frequently in females between 11 and 14 years of age.
View Article and Find Full Text PDFRadiol Case Rep
July 2025
Department of Sports and Wellness Clinic, The Jikei University School of Medicine, Tokyo, Japan.
Herein, we report a case of focal periphyseal edema in a 12-year-old female tennis player. The onset of chronic knee pain in adolescents has differential diagnoses, including fatigue fracture, epiphysis (Osgood-Schlatter disease), growth plate injury, Brodie abscess, patella-femoral malalignment, neoplasia, and meniscus tears. In this case, magnetic resonance imaging revealed focal bone marrow edema around the center of the epiphyseal plate of the distal femur.
View Article and Find Full Text PDFSemin Musculoskelet Radiol
August 2024
Section of Musculoskeletal Imaging, Department of Radiology, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania.
Skeletal Radiol
November 2024
Department of Radiology, Boston Children's Hospital, Harvard Medical School, 300 Longwood Ave, Boston, MA, 02115, USA.
Objective: To identify MRI findings that can indicate chronic physeal stress injury and differentiate it from acute Salter-Harris (SH) fracture of the pediatric knee or wrist.
Methods: IRB-approved retrospective study of consecutively selected knee and wrist MRIs from 32 athletes with chronic physeal stress injury and 30 children with acute SH fracture. MRI characteristics (physeal patency, physeal thickening, physeal signal intensity (SI), continuity of the zone of provisional calcification (ZPC), integrity of the periosteum and/or perichondrium, pattern of periphyseal and soft tissue edema signal, and joint effusion) were compared.
J Rheumatol
September 2023
Rheumatology Department, CHU de Poitiers, and University of Poitiers, LITEC, Poitiers, France.