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Importance: It is crucial to understand the psychometric properties of performance-based assessments of functional cognition to support their use and the interpretation of the outcomes.
Objective: To investigate the psychometric properties of performance-based assessments of functional cognition in adults.
Data Sources: A literature search was conducted in the MEDLINE, Embase, CINAHL, PsycINFO, Web of Science, and Scopus databases from inception to July 2022.
Study Selection And Data Collection: We searched for studies that investigated the psychometric properties of the 25 assessments identified in Part 1 of this review. The included studies examined at least one psychometric property in adults older than age 18 yr. We evaluated psychometric evidence using the COnsensus-based Standards for the selection of health Measurement INstruments (COSMIN) approach.
Findings: The most extensively researched psychometric property was hypothesis testing for construct validity, including convergent and discriminative validity. The original Allen Cognitive Level Screen, the Kitchen Task Assessment, the Menu Task, and the original Observed Tasks of Daily Living have high evidence of sufficient construct validity. The hospital-based Multiple Errands Test has moderate evidence for sufficient reliability. However, the reported evidence for other psychometric properties, including structural validity, is limited. Additionally, no studies investigated measurement error and responsiveness. No studies were deemed to satisfy the standards for establishing cross-cultural validity suggested by the COSMIN approach.
Conclusions And Relevance: Although several assessments demonstrate sufficient construct validity, additional studies are needed to elucidate other psychometric properties, including structural validity, reliability, and responsiveness, to support the use and interpretation of assessments of functional cognition in adults. Plain-Language Summary: Functional cognition refers to the integration of cognitive skills during the performance of everyday activities. We investigated whether the existing performance-based assessments of functional cognition in adults are valid and reliable. The findings of this review indicate that certain assessments, such as the original Allen Cognitive Level Screen, the Kitchen Task Assessment, the Menu Task, and the original Observed Tasks of Daily Living, may be valid. However, additional studies are needed to elucidate other psychometric properties, including reliability, structural validity and responsiveness, to support the use and interpretation of the assessments of functional cognition in adults.
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http://dx.doi.org/10.5014/ajot.2025.050949 | DOI Listing |
JAMA Neurol
September 2025
Translational Neuropathology Research Laboratory, Department of Pathology and Laboratory Medicine, Perelman School of Medicine at the University of Pennsylvania, Philadelphia.
Importance: Exposure to fine particulate matter air pollution (PM2.5) may increase risk for dementia. It is unknown whether this association is mediated by dementia-related neuropathologic change found at autopsy.
View Article and Find Full Text PDFJAMA Pediatr
September 2025
Department of Pediatrics and Emergency Medicine, Children's National Hospital, George Washington University, Washington, DC.
Importance: Adolescents account for almost half of the 2.5 million diagnosed sexually transmitted infections in the US annually, and the emergency department functions as the primary source of health care for many adolescents. No recommendations exist for emergency department gonorrhea and chlamydia screening.
View Article and Find Full Text PDFJAMA Netw Open
September 2025
Department of Social Epidemiology, Graduate School of Medicine and School of Public Health, Kyoto University, Kyoto, Japan.
Importance: Previous studies have suggested that social participation helps prevent depression among older adults. However, evidence is lacking about whether the preventive benefits vary among individuals and who would benefit most.
Objective: To examine the sociodemographic, behavioral, and health-related heterogeneity in the association between social participation and depressive symptoms among older adults and to identify the individual characteristics among older adults expected to benefit the most from social participation.
J Gerontol A Biol Sci Med Sci
September 2025
Institute of Epidemiology and Medical Biometry, Ulm University, Ulm, Germany.
Background: Ambulatory older residents in long-term care(LTC) have the highest risk of falling. However, the relationship between ambulatory activity (steps per day) and fall risk in LTC is unclear. This study examined whether baseline daily step count, functional capacity and cognitive function predicted falls in LTC residents, and whether functional capacity modified the relationship between step count and fall risk.
View Article and Find Full Text PDFMetab Brain Dis
September 2025
Department of Pharmacology and Toxicology, Faculty of Pharmacy, Cairo University, Cairo, Egypt.
Acute or chronic liver damage can result in Hepatic Encephalopathy (HE), a potentially fatal neuropsychiatric condition that leads to cerebral and neurological alterations. Dapagliflozin (DAPA), an orally active Sodium/Glucose cotransporter 2 inhibitor with long duration of action. The study aim was to evaluate the potential protective impact of DAPA against HE caused by Thioacetamide (TAA) in rats.
View Article and Find Full Text PDF