Category Ranking
98%
Total Visits
921
Avg Visit Duration
2 minutes
Citations
20
Article Abstract
Septic arthritis in native joints due to extended-spectrum beta-lactamase (ESBL)-producing bacteria is rare, and there is limited information in the current literature. An 85-year-old woman with rheumatoid arthritis experienced persistent left knee pain and mobility issues for several days. Initially, the patient was diagnosed with pseudogout by calcium pyrophosphate deposition and leukocytes in the aspiration fluid. However, joint puncture fluid culture on admission revealed the presence of ESBL-producing , whereas magnetic resonance imaging showed effusion in the left knee joint and abnormal signal changes in the surrounding soft tissue. Cefmetazole was administered and the patient underwent orthopedic surgery involving arthritis scraping, debridement, and drainage. Post-intervention, she experienced alleviation of knee pain, leading to transfer to a rehabilitation facility on the 35th day of hospitalization. This case highlights an unusual septic arthritis case caused by ESBL-producing bacteria in a nonprosthetic pseudogout-affected joint, underscoring cefmetazole's therapeutic potential.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC12136908 | PMC |
| http://dx.doi.org/10.1016/j.idcr.2025.e02262 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Synovial MS4A4A correlates with inflammation and counteracts response to corticosteroids in arthritis.
Proc Natl Acad Sci U S A
September 2025
Centre for Experimental Medicine & Rheumatology, William Harvey Research Institute and Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London EC1M 6BQ, United Kingdom.
MS4A4A belongs to the MS4A tetraspan protein superfamily and is selectively expressed by the monocyte-macrophage lineage. In this study, we aimed to evaluate the role of MS4A4A+ macrophages in rheumatoid arthritis (RA) pathogenesis and response to treatment. RNA sequencing and immunohistochemistry of synovial samples from either early treatment-naïve or active chronic RA patients showed that MS4A4A expression positively correlated with synovial inflammation.
View Article and Find Full Text PDFOsteoarthritis Flare-up Secondary to Zoledronic Acid Infusion: A Case Report.
Oman Med J
March 2025
Department of Family Medicine and Public Health, Sultan Qaboos University, Sultan Qaboos University Hospital, Oman.
Zoledronic acid is commonly used to treat osteoporosis and it is generally well tolerated. We describe the case of a woman with osteoporosis, who developed a flare-up of osteoarthritis hours after receiving a single dose of zoledronic acid. She developed fever with chills, generalized body aches, and severe low back pain.
View Article and Find Full Text PDFInvestigating multimorbidity trajectories in people living with MASLD diagnosis: A trajectory analysis using the UK Biobank.
Diabetes Obes Metab
September 2025
Phase I Clinical Trial Research Ward, The Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi Province, People's Republic of China.
Background: Metabolic dysfunction-associated steatotic liver disease (MASLD) is an emerging global health concern, and its presence increases the risk of multi-system diseases. This study aimed to investigate the multimorbidity trajectories of chronic diseases in people living with MASLD.
Methods: We identified 137 859 MASLD patients in UK Biobank and used 'propensity score matching' to match an equal number of non-MASLD controls.
Scrotal Cellulitis in the Setting of IL-17A Inhibitor Therapy: A Case Report.
Cureus
September 2025
Medicine, University of Arizona College of Medicine, Phoenix, USA.
Ixekizumab, an IL-17A inhibitor, is commonly used to treat moderate-to-severe plaque psoriasis and psoriatic arthritis, with a well-documented risk of mucocutaneous infections, though its role in bacterial infections is less defined. We present the case of a 62-year-old male on ixekizumab who developed scrotal cellulitis with subsequent septic thrombophlebitis, despite no clear entry point. His condition initially improved with broad-spectrum antibiotics, but later worsened, requiring further imaging and multidisciplinary management.
View Article and Find Full Text PDFSeptic Shock After Surgery in Arnold-Chiari Malformation Type I: A Case Report.
Int Med Case Rep J
August 2025
Emergency and Trauma Care Research Center, Imam Reza General Hospital, Tabriz University of Medical Sciences, Tabriz, Iran.
Background: Arnold-Chiari Malformation Type I (ACM-I) is a congenital disorder that can lead to severe neurological symptoms. While decompression surgery is the standard treatment, postoperative complications such as cerebrospinal fluid (CSF) leakage and infections can result in critical outcomes. Here, we report a case of septic shock following decompression surgery in a patient with ACM-I, emphasizing the challenges in postoperative critical care management.
View Article and Find Full Text PDF