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Numerous studies report sex differences in the prevalence of problem gambling (PG), but the etiological basis of these differences across recognized risk factors is unclear. Data from a large, nationally-stratified Canadian survey (n = 10,044) were used to explore whether sex moderates relationships between PG and its risk factors, including (1) gambling participation, (2) gambling motivations, (3) mental health, and (4) substance use. The sample was 53.6% female, had a mean age of 52.4 years (SD = 15.4), and 61.8% had Northern/Western European heritage. The magnitude of the relationship between sixteen (44%) study variables and PG varied between sexes, though these effects were generally small. These variables include: (1) past month participation in lotteries, electronic gambling machines, sports betting, bingo, and financial speculation; (2) all measures of gambling intensity (breadth, frequency, expenditure); (3) enhancement and coping motivations for gambling; and (4) five additional substance use and mental health variables. With the exception of past month bingo participation, posttraumatic stress disorder, history of substance-related problems, negative life events, and impulsivity, these effects were larger for females relative to males. Finally, multivariate analyses revealed notable differences in the risk factors for PG, with variation in male PG being uniquely explained by gambling to develop skill, substance use disorder, negative life events, and age, and variation in female PG being uniquely explained by online gambling, breadth of gambling involvement, and coping motives. These findings highlight potential sex-specific pathways to PG that should be the subject of future research.
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http://dx.doi.org/10.1007/s10899-025-10404-z | DOI Listing |
Public Health
September 2025
Department of Public Health, Erasmus MC University Medical Center, Rotterdam, the Netherlands.
Objectives: Participation rates in fecal immunochemical test (FIT)-based colorectal cancer (CRC) screening differ across socio-demographic subgroups. The largest health gains could be achieved in subgroups with low participation rates and high risk of CRC. We investigated the CRC risk within different socio-demographic subgroups with low participation in the Dutch CRC screening program.
View Article and Find Full Text PDFTurk J Pediatr
September 2025
Division of Allergy and Asthma, Department of Pediatrics, Faculty of Medicine, Hacettepe University, Ankara, Türkiye.
Animal allergens, particularly those from cats, dogs, and horses, are significant risk factors for the development of allergic diseases in childhood. Managing animal allergies requires allergen avoidance and, when this is not feasible, specific immunotherapy. Patient history remains the cornerstone of diagnosis, providing the foundation for diagnostic algorithms.
View Article and Find Full Text PDFTurk J Pediatr
September 2025
Department of Cardiorespiratory Physiotherapy and Rehabilitation, Faculty of Physical Therapy and Rehabilitation, Hacettepe University, Ankara, Türkiye.
Background: Vascular changes are observed in children with cystic fibrosis (cwCF), and gender-specific differences may impact arterial stiffness. We aimed to compare arterial stiffness and clinical parameters based on gender in cwCF and to determine the factors affecting arterial stiffness in cwCF.
Methods: Fifty-eight cwCF were included.
JMIR Res Protoc
September 2025
University of Nevada, Las Vegas, Las Vegas, NV, United States.
Background: In-hospital cardiac arrest (IHCA) remains a public health conundrum with high morbidity and mortality rates. While early identification of high-risk patients could enable preventive interventions and improve survival, evidence on the effectiveness of current prediction methods remains inconclusive. Limited research exists on patients' prearrest pathophysiological status and predictive and prognostic factors of IHCA, highlighting the need for a comprehensive synthesis of predictive methodologies.
View Article and Find Full Text PDFJ Pediatr Hematol Oncol
September 2025
Division of Pediatric Hematology-Oncology, Mayo Clinic Children's, Rochester, MN.
Post-transplant lymphoproliferative disorder is a rare and serious complication of organ and stem cell transplant secondary to immunosuppressive therapies, most commonly of monomorphic B-cell subtype. Here we describe the first reported case of a pediatric heart transplant patient who developed both monomorphic B-cell and nondestructive PTLD with plasmacytic hyperplasia followed by an unrelated case of monomorphic T-cell and nondestructive PTLD with plasmacytic hyperplasia, which later relapsed. We detail the patient's risk factors for development of PTLD and her successful treatment regimens.
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