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http://dx.doi.org/10.1016/j.bneo.2024.100027 | DOI Listing |
Int J Health Care Qual Assur
September 2025
Department of Electrical and Computer Engineering, Graduate University of Advanced Technology, Kerman, Iran.
Purpose: Neonatal mortality is a significant global health issue, particularly in low- and middle-income countries. This study aims to identify and understand the factors contributing to high neonatal mortality rates in the cities of Kerman and Bam, Iran, to develop effective strategies for improvement.
Design/methodology/approach: We employed systems dynamics to develop Causal Loop Diagrams that capture qualitative interactions among determinants of neonatal mortality.
Front Bioeng Biotechnol
August 2025
Institute of Process Engineering in Life Sciences, Section IV: Biomolecular Separation Engineering, Karlsruhe Institute of Technology (KIT), Karlsruhe, Germany.
Spectroscopic soft sensors are developed by combining spectral data with chemometric modeling, and offer as Process Analytical Technology (PAT) tools powerful insights into biopharmaceutical processing. In this study, soft sensors based on Raman spectroscopy and linear or partial least squares (PLS) regression were developed and successfully transferred to a filtration-based recovery step of precipitated virus-like particles (VLPs). For near real-time monitoring of product accumulation and precipitant depletion, the dual-stage cross-flow filtration (CFF) set-up was equipped with an on-line loop in the second membrane stage.
View Article and Find Full Text PDFACS Omega
September 2025
Shandong Provincial Key Laboratory of Oil, Gas and New Energy Storage and Transportation Safety, China University of Petroleum, Qingdao, Shandong 266580, People's Republic of China.
The natural gas pipeline network has a complex topology with variable flow directions, and the supply demand relationships between nodes exhibit cyclical, fluctuating, and time-varying trends. Developing efficient, accurate, and fast intelligent control algorithms is crucial for optimizing the distribution of natural gas networks. Analyzing the operational data from a provincial network over three years revealed that abnormal flow data, such as supply interruptions due to incidents, early fulfillment of supply, and insufficient flow distribution, can cause deviations between the actual transmission volume and the planned transmission volume predicted by the uneven coefficient method.
View Article and Find Full Text PDFJ Eval Clin Pract
September 2025
Department of Orthopedics and Traumatology, Medical Faculty, University of Health Sciences, Antalya, Turkey.
Aims And Objective: The field of medical statistics has experienced significant advancements driven by integrating innovative statistical methodologies. This study aims to conduct a comprehensive analysis to explore current trends, influential research areas, and future directions in medical statistics.
Methods: This paper maps the evolution of statistical methods used in medical research based on 4,919 relevant publications retrieved from the Web of Science.
J Cereb Blood Flow Metab
September 2025
Department of Psychiatry and Psychotherapy, Medical University of Vienna, Vienna, Austria.
Functional PET (fPET) identifies stimulation-specific changes of physiological processes, individual molecular connectivity and group-level molecular covariance. Since there is currently no consistent analysis approach available for these techniques, we present a toolbox for unified fPET assessment. The toolbox supports analysis of data obtained with a variety of radiotracers, scanners, experimental protocols, cognitive tasks and species.
View Article and Find Full Text PDF