98%
921
2 minutes
20
Social network-based adolescent substance use interventions have demonstrated potential for reducing adolescent cigarette smoking. This approach is premised upon leveraging youths' social networks for the diffusion of peer influence. Determining which adolescents to select in network interventions for reducing smoking is a major consideration. We utilize a simulation approach that first estimates Stochastic Actor-Oriented models (SAOM) of adolescent smoking using data from two of the largest schools from the longitudinal saturation sample of the National Study of Adolescent to Adult Health (Add Health) (n = 3,154). We then conduct Agent-Based Simulation models which mimic the consequences of intervention strategies selecting adolescents in network positions and structures that are salient for smoking and the diffusion of peer influence within school-based networks, and we select adolescents smoking at different levels. Our findings indicate that selecting adolescents occupying central network positions yielded the greatest reductions in the number of smokers in a school, one year post intervention. Moreover, our findings indicate that in the school with the higher smoking prevalence, there was a beneficial network multiplier effect one year later, which resulted in more non-smokers than those smokers initially intervened upon. When examining the effects of varying the magnitude of peer influence, we find that targeting central positions in networks led to even greater decreases in smoking in schools with higher levels of peer influence. Our findings highlight interdependence and sensitivity of peer influence to network position and have implications for informing school-based network interventions for adolescent smoking.
Download full-text PDF |
Source |
---|---|
http://dx.doi.org/10.1016/j.socscimed.2025.118196 | DOI Listing |
Arch Pharm Res
September 2025
College of Pharmacy and Medical Research Center, Chungbuk National University, 194-21, Osongsaengmyeong 1-ro, Osong-eup, Cheongju-si, Chungcheongbuk-do, 28160, Republic of Korea.
Atopic dermatitis (AD) is an inflammatory skin disease that produces a variety of inflammatory cytokines and chemokines. Chitinase-3-like protein 1 (CHI3L1, YKL-40) significantly contributes to AD-associated inflammatory response and is highly expressed in patients with AD. Therefore, this study elucidated the effects and potential mechanisms of human YKL-40 antibody on AD-affected skin.
View Article and Find Full Text PDFCancer Med
September 2025
Department of Radiology & Nuclear Medicine, Erasmus MC - University Medical Centre Rotterdam, Rotterdam, the Netherlands.
Aims: This review summarizes the role and future prospects of nuclear medicine in ovarian cancer, focusing on novel radiopharmaceuticals beyond FDG for diagnostic, predictive, and therapeutic applications within a theranostic framework.
Materials And Methods: A narrative literature review was conducted using major databases. Peer-reviewed articles addressing non-FDG radiopharmaceuticals in ovarian cancer were identified and assessed; FDG-based studies were excluded due to the availability of prior comprehensive reviews.
Lancet Reg Health West Pac
August 2025
Western Australian Centre for Rural Health, University of Western Australia, 167 Fitzgerald Street, Geraldton, Western Australia, 6530, Australia.
Poorer cancer prevention and control outcomes for First Nations Australians have resulted in a need for improved health literacy, that is their capacity as individuals to access, understand, and use information in ways that promote and maintain good health. This narrative review explores the evidence on how education programs work to improve First Nations Australians' understanding of cancer, and how this leads to more effective use of prevention, screening and treatment services. Limited to the Australian context, a bibliographic search using terms structured around four main concepts: Aboriginal, Cancer, Australia, and Intervention (health literacy, health promotion) was undertaken in May 2024 for publications from January 2000.
View Article and Find Full Text PDFPediatr Obes
September 2025
Clinical Developmental Psychology, Ghent University, Ghent, Belgium.
Intra-familial weight stigma is a subtle yet impactful dynamic that may influence the outcomes of family-based interventions aimed at treating childhood obesity. While much attention has been paid to societal and peer-related weight stigma, less focus has been placed on how stigma manifests within families. This position statement highlights the importance of recognising that such stigma can unintentionally arise in the home.
View Article and Find Full Text PDFBMJ Open
September 2025
Radiotherapy Department, Charing Cross Hospital, Imperial College Healthcare NHS Trust, London, England, UK.
Introduction: There are estimated to be 3.4 million patients in the UK living after a diagnosis of cancer. We know very little about their quality of life or healthcare usage.
View Article and Find Full Text PDF