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Recent advancements in embolic agents and endovascular techniques have led to increased interest in exploring endovascular embolization as a viable treatment for brain arteriovenous malformations. Several trials have investigated the use of various embolic agents for the treatment of arteriovenous malformations (AVMs) endovascularly. However, the reporting outcomes and design elements in these studies are heterogeneous and include inclusion/exclusion criteria and evaluated endpoints. This scoping review synthesized common endpoints cited within embolic endovascular AVM trials for monitoring their safety and efficacy, with a commentary on common threads of focus in future trials for evaluating AVM treatment, including adapting designs to be on par with the pace of advancements in endovascular technologies.
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC12121930 | PMC |
http://dx.doi.org/10.7759/cureus.83197 | DOI Listing |
Neurol Sci
September 2025
Department of Neurosurgery, Fondazione Policlinico Universitario A. Gemelli IRCCS, Università Cattolica del Sacro Cuore, Rome, Italy.
Background: Hereditary Hemorrhagic Telangiectasia (HHT) is an autosomal dominant disorder characterized by abnormal vascular formations across multiple organ systems, including the brain. While arteriovenous malformations (AVMs) are well recognized in HHT, non-AVM cerebrovascular malformations remain underreported and poorly understood manifestations of the disease.
Methods: A systematic review was conducted using multiple databases, applying a two-step screening process to exclude studies with insufficient, irrelevant, or incomplete data.
Khirurgiia (Mosk)
September 2025
Mandryka Central Military Clinical Hospital, Moscow, Russia.
Widespread fragmentation shells in combat operations with frequent multiple damage to organs and systems force to use all available diagnostic methods for treating severe injuries including lesion of great vessels of extremities. One of the consequences of these lesions is arteriovenous fistula (AVF). The last one may be asymptomatic at first.
View Article and Find Full Text PDFJTCVS Open
August 2025
Division of Cardiothoracic Surgery, Children's Hospital of Philadelphia, Philadelphia, Pa.
[This corrects the article DOI: 10.1016/j.xjon.
View Article and Find Full Text PDFJ Int Med Res
September 2025
Department of Otolaryngology Head and Neck surgery, Hangzhou First People's Hospital, Westlake University, China.
Characterized by abnormalities of the blood vessel wall, hereditary hemorrhagic telangiectasia is an autosomal dominant disorder. Recurrent or spontaneous epistaxis is the most prevalent symptom of hereditary hemorrhagic telangiectasia, whose severity varies greatly, ranging from moderate self-limiting epistaxis to severe, life-threatening epistaxis, which often requires multiple treatments and is therefore a challenge for otorhinolaryngologists. This case report retrospectively analyzed the clinical data and family history of a patient who presented to the Department of Otorhinolaryngology, Hangzhou First People's Hospital, with recurrent epistaxis for 60 years.
View Article and Find Full Text PDFInterv Neuroradiol
September 2025
J.J. Merland Department of Therapeutic Neuroangiography, University General Hospital of Catalonia and Hospital del Mar, Barcelona, Spain.
Background and purposeThis study presents our initial experience using Obtura, a novel nonadhesive liquid embolic agent with extra-low viscosity variants, in transvenous curative embolization of brain arteriovenous malformations (bAVMs). We assess the agent's performance and compare its advantages with other extra-low viscosity options currently available.Materials and methodsFive patients (three females, two males; mean age, 33 years; range, 20-55 years) with ruptured bAVMs were treated using the transvenous retrograde pressure cooker technique (TVRPCT).
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