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Spontaneous coronary artery dissection (SCAD) is a rare but underrecognized cause of acute coronary syndrome. It is mostly reported in female patients. In this report, however, we describe this rare and unique case of multivessel SCAD in a 52-year-old man. He was presented with chest pain, significant elevated cardiac troponin level, and T-wave changes in electrocardiogram. Coronary angiography showed multivessel SCAD involving his circumflex and right coronary arteries. The patient was conservatively managed. He has recovered well and was discharged a week after admission. Coronary angiography is still considered the gold standard for diagnosis of multivessel SCAD. Conservative treatment is recommended in most conditions unless there is a necessity for interventional treatment.
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http://dx.doi.org/10.1002/ccd.31656 | DOI Listing |
Magn Reson Imaging
October 2025
Department of Radiology, Affiliated Hospital of Yangzhou University, Yangzhou University, Yangzhou 225001, China. Electronic address:
Objective: To evaluate the myocardial ischemic segments and related factors in stable coronary artery disease (SCAD) patients by native T1 mapping.
Methods: 316 SCAD patients and 30 healthy controls (all right coronary dominant) underwent CMR native T1 mapping within 90 days of CCTA. Segmental native T1 values were measured using AHA 16-segment model.
Radiol Case Rep
September 2025
Radiology Department, Cork University Hospital, Wilton, Cork, T12 DC4A, Ireland.
We describe a case of a 38-year-old woman who presented with acute pleuritic chest pain following 3 days of emesis. There was a significant rise in troponin-I, consistent with a non-ST-segment elevation myocardial infarction (NSTEMI). Coronary angiography demonstrated a probable spontaneous coronary artery dissection (SCAD) with intramural haematoma of the left anterior descending (LAD) artery.
View Article and Find Full Text PDFCatheter Cardiovasc Interv
August 2025
Department of Cardiology, The First Affiliated Hospital of Ji'nan University, Guangzhou, China.
Spontaneous coronary artery dissection (SCAD) is a rare but underrecognized cause of acute coronary syndrome. It is mostly reported in female patients. In this report, however, we describe this rare and unique case of multivessel SCAD in a 52-year-old man.
View Article and Find Full Text PDFJACC Adv
May 2025
Baim Institute for Clinical Research, Boston, Massachusetts, USA; Department of Cardiology, Radboud University Medical Center, Nijmegen, the Netherlands; Noordwest Ziekenhuisgroep, Alkmaar, The Netherlands.
Background: The AEGIS-II (ApoA-I Event Reducing in Ischemic Syndromes-II; NCT03473223) trial evaluated CSL112, a human plasma-derived apolipoprotein A-I therapy, for reducing cardiovascular events after acute myocardial infarction (AMI). Given CSL112's potential anti-inflammatory properties, we conducted an exploratory post hoc analysis to determine if its efficacy is influenced by baseline neutrophil-lymphocyte ratio (NLR), a marker of systemic inflammation, and low-density lipoprotein cholesterol (LDL-C).
Objectives: The purpose of this study was to investigate the association of baseline NLR and cardiovascular events and explore whether NLR and LDL-C modify CSL112's efficacy in post-AMI patients.
BMJ Case Rep
March 2025
Molecular Cardiology, Victor Chang Cardiac Research Institute, Darlinghurst, New South Wales, Australia
Spontaneous coronary artery dissection (SCAD) is an increasingly recognised cause of acute coronary syndrome predominantly affecting women (>90% of cases) that is frequently associated with other arteriopathies, such as fibromuscular dysplasia (FMD) and migraine. We present a case of multi-vessel SCAD in a woman in her 40s presenting with myocardial infarction in whom incidental widespread FMD was found, including a massive right renal artery aneurysm requiring ex vivo resection, repair and autotransplantation. The case underscores the need for routine angiographic screening for FMD, which has a shared genetic risk with SCAD, and is associated with aneurysms, stenoses and hypertension.
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