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Background: The forces of the jaw muscles are transmitted to the dentition and the temporomandibular joints (TMJs). Imbalances in the force distribution can lead to occlusal trauma, excessive tooth wear, or TMJ osteoarthritis, making the assessment of bite force (BF) distribution clinically significant. Existing thin-film BF measurement devices capture the magnitudes of a system of BFs distributed at multiple occlusal contacts (OCs), but fail to capture their directional components, limiting their clinical utility. This study aimed to develop a method for representing BF systems as a wrench, a simplified force-couple model, using digital dentistry tools and to evaluate its reliability in terms of interexaminer reproducibility.
Methods: A semi-automated system was developed to integrate thin-film BF measurement data with digital models of maxillary and mandibular dental arches. BF systems were represented as wrenches with six parameters: force magnitude, axis location (x, y), axis orientation (frontal, sagittal), and pitch (moment-to-force ratio).Ten young adult participants (5 women, 5 men; mean age: 20.1 ± 2.9 years) were recruited. BF measurements were performed on all participants using the developed system. Two independent examiners manually assigned BFs to the identified OCs separately, and the reliability of these assignments was evaluated based on inter-examiner agreement. Intraclass correlation coefficients (ICCs) for wrench parameters were calculated to assess the consistency of biomechanical outcomes using appropriate statistical tests, with significance set at p < 0.05.
Results: The proposed system allowed substantial automation, and the manual steps were limited to segmenting the interocclusal record model for each mandibular tooth and assigning BFs to the identified OCs. The interexaminer agreement was evaluated for the BFs assigned to the identified OCs, which yielded an 87% match rate. Furthermore, the impact on wrench parameters was assessed using ICCs, which ranged from 0.93 to 0.99, indicating high reliability.
Conclusions: The developed system efficiently integrates BF measurements and three-dimensional OC analysis, providing a practical method for clinical evaluation of the BF systems. In addition, the system provided consistent outcomes in biomechanical analyses across different examiners.
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http://dx.doi.org/10.1186/s12903-025-06191-z | DOI Listing |
Gait Posture
September 2025
Department of Anatomy and Medical Imaging, University of Auckland, Auckland, New Zealand.
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September 2025
Mechanical and Nuclear Engineering Department, Khalifa University of Science and Technology, Abu Dhabi, United Arab Emirates.
Sectionally nonlinearly functionally graded (SNFG) structures with triply periodic minimal surface (TPMS) are considered ideal for bone implants because they closely replicate the hierarchical, anisotropic, and porous architecture of natural bone. The smooth gradient in material distribution allows for optimal load transfer, reduced stress shielding, and enhanced bone ingrowth, while TPMS provides high mechanical strength-to-weight ratio and interconnected porosity for vascularization and tissue integration. Wherein, The SNFG structure contains sections with thickness that varies nonlinearly along their length in different patterns.
View Article and Find Full Text PDFmBio
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Fred Hutchinson Cancer Center, Vaccine and Infectious Disease Division, Seattle, Washington, USA.
Accurate timing estimates of when participants acquire HIV in HIV prevention trials are necessary for determining antibody levels at acquisition. The Antibody-Mediated Prevention (AMP) Studies showed that a passively administered broadly neutralizing antibody can prevent the acquisition of HIV from a neutralization-sensitive virus. We developed a pipeline for estimating the date of detectable HIV acquisition (DDA) in AMP Study participants using diagnostic and viral sequence data.
View Article and Find Full Text PDFBackground: Cytomegalovirus (CMV) viremia is a critical concern and known by the presence of the virus DNA in the blood, which poses sever risks and develops many complications in immuno-compromised patients. When CMV is untreated, it can cause pneumonitis, colitis, hepatitis, and encephalitis. Current diagnosis relies on molecular methods with qPCR as the preferred method.
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