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Background: Intravascular lithotripsy (IVL) is currently recommended for heavily calcified coronary lesions with an optical coherence tomography (OCT)- or intravascular ultrasound (IVUS)-based calcium score of 3 or 4.
Methods And Results: We retrospectively assessed both calcium scores for the same lesions, which had a heavily calcified coronary lesion requiring plaque modification. Among 52 lesions, the mean OCT-based calcium score was 3.96, whereas the mean IVUS-based calcium score was 2.15 (P<0.001).
Conclusions: This comparative study revealed a significant discrepancy between IVUS- and OCT-based calcium scores in heavily calcified coronary lesions, which may influence treatment strategies, including use of IVL.
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http://dx.doi.org/10.1253/circj.CJ-25-0068 | DOI Listing |
Quant Imaging Med Surg
September 2025
Department of Radiology, State Key Laboratory of Complex Severe and Rare Diseases, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Background: Super-resolution deep learning reconstruction (SR-DLR) algorithm has emerged as a promising image reconstruction technique for improving the image quality of coronary computed tomography angiography (CCTA) and ensuring accurate CCTA-derived fractional flow reserve (CT-FFR) assessments even in problematic scenarios (e.g., the presence of heavily calcified plaque and stent implantation).
View Article and Find Full Text PDFCardiovasc Interv Ther
August 2025
Department of Cardiology, Teikyo University Hospital, Itabashi, Japan.
Performing percutaneous coronary intervention (PCI) for heavily calcified coronary lesions remains a significant clinical challenge. In 2023, following the availability of intravascular lithotripsy (IVL), a consensus document was published outlining imaging-guided device selection strategies for the treatment of calcified lesions. Since the publication of that document, the DUAL-PREP study has demonstrated the safety of combining rotational atherectomy (rotablator) with IVL, a strategy previously contraindicated in the original consensus.
View Article and Find Full Text PDFAnn Cardiol Angeiol (Paris)
September 2025
Groupe Hospitalier Mutualiste de Grenoble, 8 rue du Dr Calmette, 38000 Grenoble, France. Electronic address:
Coronary artery calcification is highly prevalent in elderly patients and poses significant challenges during percutaneous coronary intervention (PCI). We report the case of an 86-year-old man admitted for ST-elevation myocardial infarction. Coronary angiography revealed triple-vessel disease with an acute coronary artery occlusion, a long, heavily calcified proximal-to-mid left anterior descending artery stenosis, and a severely calcified proximal circumflex lesion.
View Article and Find Full Text PDFProc Biol Sci
August 2025
School of Geosciences, University of Edinburgh, Edinburgh, Scotland, UK.
The Sinsk Event (approx. 513.5 million years ago, Ma) is the first Phanerozoic mass extinction, marking the end of the canonical Cambrian Radiation.
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