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http://dx.doi.org/10.1016/j.jacep.2025.02.046 | DOI Listing |
Brain Behav
September 2025
Department of Neurology, Huai'an First People's Hospital, the Affiliated Huai'an No. 1 People's Hospital of Nanjing Medical University, Huai'an, Jiangsu, China.
Background And Purpose: Parkinson's disease (PD), a prevalent neurodegenerative disorder characterized by motor impairments, frequently accompanied by neuropsychiatric symptoms that significantly impair daily functioning and quality of life. The present study aimed to assess the efficacy of botulinum toxin A (BTX-A) in alleviating neuropsychiatric symptoms among PD patients.
Methods: This is an open-label, nonrandomized controlled trial.
J Vis Exp
August 2025
Department of Computer Science and Engineering, Gokaraju Rangaraju Institute of Engineering and Technology, Hyderabad, India.
Deepfakes pose critical threats to digital media integrity and societal trust. This paper presents a hybrid deepfake detection framework combining Convolutional Neural Networks (CNNs) and Generative Adversarial Networks (GANs) to address challenges in scalability, generalizability, and adversarial robustness. The framework integrates adversarial training, a temporal decay analysis model, and multimodal detection across audio, video, and text domains.
View Article and Find Full Text PDFIEEE Trans Biomed Eng
September 2025
Objective: Transcranial ultrasound (US) stimulation (TUS) has emerged as a promising technique for minimally invasive, localized, deep brain stimulation. However, indirect auditory effects during neuromodulation require careful consideration, particularly in experiments with rodents. One method to prevent auditory responses involves applying tapered envelopes to US bursts.
View Article and Find Full Text PDFNew Phytol
September 2025
Department of Ecology & Evolution, University of Chicago, Chicago, IL, 60637, USA.
Understanding the rate and nature of adaptation is crucial for managing biodiversity across our changing landscapes. This perspective synthesizes insights from resistance evolution - a case of rapid, repeated adaptation to extreme human-mediated selection - to reveal how adaptive genetic architectures determine and feedback with evolutionary dynamics. Recent population genomic and quantitative genetic approaches have demonstrated that the extent of genetic parallelism and reliance on de novo vs standing genetic variation can vary with the complexity of genetic architectures.
View Article and Find Full Text PDFBioscience
September 2025
South African National Biodiversity Institute, Kirstenbosch Research Centre, Cape Town.
Conservation policies often need to integrate scientific predictions with ethical considerations. However, different normative ethical systems at the root of conservation approaches often support different decisions, and the moral stances of stakeholders are influenced by diverse societal values and perceptions. This creates the potential for dilemmas and conflicts.
View Article and Find Full Text PDF