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Background And Aims: The Dinga Dinga Virus (DDV) has emerged as a mysterious disease gripping women in Uganda, raising alarm due to its unusual and distressing "dancing" like symptoms. These symptoms, characterized by involuntary movements resembling dance, suggest possible neurological involvement, though the exact pathogen remains unidentified. The causative agent for DDV is still unknown. We hypothesized that the possible microorganism could be a virus, bacteria, or vector-borne origin. Therefore, comprehensive research is urgently needed to confirm its cause.
Methods: We performed a comprehensive literature search in Scopus and Web of Science related to the different outbreaks of viruses. We collected relevant information from appropriate articles for this review.
Results: The unique representation of the disease is spreading rapidly in localized areas that have the potential to escalate into a broader public health crisis. Preventive measures focused on symptom monitoring, public awareness, and isolation of suspected cases to limit transmission. Authorities emphasize hygiene practices, using personal protective equipment (PPE), and early reporting to manage the outbreak effectively. Simultaneously, global health organizations are being called to collaborate on diagnostic development, therapeutic interventions, and vaccine research. The disproportionate impact on women has brought social and cultural dynamics into the spotlight, as stigma and misinformation exacerbate the outbreak's challenges. Immediate and long-term strategies must address these aspects by strengthening healthcare infrastructure and enhancing disease surveillance systems.
Conclusion: As the world recovers from the COVID-19 pandemic, the DDV is a stark reminder of the ongoing threat of emerging infectious diseases. Proactive, science-driven efforts are critical to understanding and mitigating this enigmatic disease, ensuring it does not escalate into another global health crisis.
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http://dx.doi.org/10.1002/hsr2.70836 | DOI Listing |
Diagn Microbiol Infect Dis
October 2025
Research and Development Cell (RDC), Parul University, Waghodia, Vadodara, Gujarat, 391760, India; Department of Biotechnology, Parul Institute of Applied Sciences, Parul University, Waghodia, Vadodara, Gujarat, 391760, India. Electronic address:
Dinga Dinga fever, a novel illness in Bundibugyo district of Uganda, causes uncontrollable tremors, fever and fatigue, primarily in women and girls. Though non-fatal, it disrupts communities. The present article explores its symptoms, epidemiology and ongoing investigations, emphasizing interdisciplinary approaches and public health interventions while drawing comparisons to historical Dancing Plagues.
View Article and Find Full Text PDFVaccine
July 2025
School of Global Health and Bioethics, Euclid University, Bangui, Central African Republic. Electronic address:
Introduction: Malaria is a life-threatening mosquito-borne disease. This significant public health problem disproportionately affects people in Africa. Despite investments in existing vector control and curative treatments, malaria remains the first infant-child morbidity and mortality cause, with 11,000 annual deaths in Cameroon.
View Article and Find Full Text PDFBackground And Aims: The Dinga Dinga Virus (DDV) has emerged as a mysterious disease gripping women in Uganda, raising alarm due to its unusual and distressing "dancing" like symptoms. These symptoms, characterized by involuntary movements resembling dance, suggest possible neurological involvement, though the exact pathogen remains unidentified. The causative agent for DDV is still unknown.
View Article and Find Full Text PDFChemistry
June 2025
Institute for Optical Technologies, Muenster University of Applied Sciences, 48565, Steinfurt, Germany.
Singlet dioxygen (O) plays a pivotal role as the active agent in photodynamic therapy (PDT) for cancer treatment, as well as in the photo-inactivation of antibiotic-resistant microbes (antimicrobial photodynamic therapy, aPDT). The ability to sensitively monitor the production and behavior of ¹O₂ following its photo-catalytic generation is crucial for developing effective therapeutic strategies. Optical sensor molecules that respond to ¹O₂ through changes in absorption or, more sensitively, fluorescence, are suitable choices.
View Article and Find Full Text PDFDiseases
April 2025
Rollins School of Public Health, Emory University, Atlanta, GA 30322, USA.
In recent decades, malaria has become a major worldwide public health problem in endemic countries, especially with children below five years. Malaria causes inflammation, and inflammatory biomarkers like α-1-glycoprotein (AGP) and C-reactive protein (CRP) are elevated in serum during malaria. This work aimed at assessing the serum levels of AGP (chronic inflammation) and CRP (acute inflammation) biomarkers and IgG4 and their correlation with malaria in children below five years in the Buea Health District of the South West Region of Cameroon.
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