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http://dx.doi.org/10.1186/s12931-025-03258-x | DOI Listing |
Curr Alzheimer Res
September 2025
Department of Neurology, the Wuxi No. 2 People's Hospital, Jiangnan University Medical Center, Wuxi, Jiangsu Province, China.
Introduction: The complement receptor 1 (CR1) gene is identified as the one closely associated with Alzheimer's disease (AD). However, there has been no exploration of the imaging alterations associated with the CR1 gene in AD patients of the Han population. The purpose of this study is to investigate the association between the rs6656401 mutation and neuroimaging variations in Han AD patients.
View Article and Find Full Text PDFAm J Ophthalmol
September 2025
Department of Ophthalmology, Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, Florida, USA. Electronic address:
Purpose: To report on the real-world experience of using intravitreal pegcetacoplan for the treatment of geographic atrophy (GA) in age-related macular degeneration (AMD).
Design: Retrospective interventional case series.
Methods: Eyes with symptomatic GA secondary to AMD were treated with 15mg of intravitreal pegcetacoplan and participated in an ongoing prospective swept-source optical coherence tomography angiography (SS-OCTA) imaging study.
Acta Psychol (Amst)
September 2025
Pampanga State University, Pampanga, Philippines. Electronic address:
This study investigated the effects of using the intelligent and non-intelligent versions of Ibigkas! Math-a mobile-based, computer-supported collaborative learning platform for Grade 5 mathematics on the mathematics performance of Grade 5 students. Out of 155 Grade 5 students from four universities, only 119 participated in the five consecutive-day experiment. Ethical approval was granted before data collection.
View Article and Find Full Text PDFFront Sports Act Living
August 2025
Department of Physical Activities and Health Sciences, Masaryk University, Faculty of Sports Studies, Brno, Czechia.
Introduction: Deficits in lower-limb muscle strength and altered gait mechanics are common after anterior cruciate ligament reconstruction (ACL). While isokinetic strength testing is widely accepted in return-to-sport assessment, the role of plantar pressure analysis in detecting compensatory gait strategies remains underexplored.
Methods: This study included 10 male patients (30.
Bioinformatics
September 2025
Institutional Research Core Program-Biological Data Science Core, University of Alabama at Birmingham, Birmingham, AL United States.
Motivation: Recent advancements in long-read single-cell RNA sequencing (scRNA-seq) have facilitated the quantification of full-length transcripts and isoforms at the single-cell level. Historically, long-read data would need to be complemented with short-read single-cell data in order to overcome the higher sequencing errors to correctly identify cellular barcodes and unique molecular identifiers. Improvements in Oxford Nanopore sequencing, and development of novel computational methods have removed this requirement.
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