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Background: Previous studies on the relationship between sleep duration and anxiety have yielded inconsistent results. This study aimed to explore this association using data from a large, nationally representative sample of US adults.
Methods: Data from 13,476 participants in the National Health and Nutrition Examination Survey (NHANES) 2007-2012 were analyzed. Weighted robust Poisson regression models were employed to assess the relationship between sleep duration and anxiety, with additional subgroup analyses conducted to explore variations across different demographic groups.
Results: Among participants, 25.8% exhibited symptoms of anxiety. Compared to normal sleep duration (7-9 hours), very short sleep durations (<5 hours) and short sleep durations (5 to <7 hours) were significantly linked to higher anxiety risks, with adjusted incidence rate ratios (IRRs) of 1.40 (95% CI [1.23-1.59]) and 1.17 (95% CI [1.09-1.25]), respectively. Subgroup analyses revealed that shorter sleep durations were more strongly associated with anxiety in males, older adults, racial minorities, and married individuals compared to their counterparts. Notably, long sleep duration (≥9 hours) showed no significant overall association with anxiety (IRR = 1.11 [0.95-1.29]); however, in specific subgroups such as non-married individuals and younger adults, it was linked to an increased risk of anxiety.
Conclusion: Short sleep duration is associated with an increased risk of anxiety, with the strength of this association differing notably across demographic subgroups. Long sleep duration is associated with higher anxiety risk exclusively in specific groups, including non-married individuals and younger adults. Further research is needed to uncover the mechanisms underlying these associations.
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http://dx.doi.org/10.2147/PRBM.S516062 | DOI Listing |
Ann Am Thorac Soc
September 2025
University of Florida, Department of Medicine, Gainesville, Florida, United States;
Background: Pulmonary hypertension (PH) is a systemic illness with increasingly subtle disease manifestations including sleep disruption. Patients with PH are at increased risk for disturbances in circadian biology, although to date there is no data on "morningness" or "eveningness" in pulmonary vascular disease.
Research Questions: Our group studied circadian rhythms in PH patients based upon chronotype analysis, to explore whether there is a link between circadian parameters and physiologic risk-stratifying factors to inform novel treatment strategies in patients with PH?
Study Design And Methods: We serially recruited participants from July 2022 to March 2024, administering in clinic the Munich Chronotype Questionnaire (MCTQ).
Neurology
October 2025
Department of Radiology, Mayo Clinic, Rochester, MN.
Background And Objectives: The relationship between insomnia and cognitive decline is poorly understood. We investigated associations between chronic insomnia, longitudinal cognitive outcomes, and brain health in older adults.
Methods: From the population-based Mayo Clinic Study of Aging, we identified cognitively unimpaired older adults with or without a diagnosis of chronic insomnia who underwent annual neuropsychological assessments (z-scored global cognitive scores and cognitive status) and had quantified serial imaging outcomes (amyloid-PET burden [centiloid] and white matter hyperintensities from MRI [WMH, % of intracranial volume]).
High Alt Med Biol
September 2025
Division of Pulmonary, Critical Care and Sleep Medicine, Department of Medicine, University of Washington, Seattle, Washington, USA.
Manferdelli, Giorgio, Marc M Berger, and Andrew M Luks.Ignoble Gas: The Questionable Role of Xenon in Rapid Ascents of Mount Everest. 00:00-00, 2025.
View Article and Find Full Text PDFJ Behav Addict
September 2025
2Columbia University School of Nursing, New York, NY, USA.
Background And Aims: Caffeine is the most commonly used substance during gaming sessions. Despite health guidelines to avoid caffeine before adulthood, many adolescents use caffeine to compensate for lost sleep or prolong wakefulness to enhance gaming performance. The relationship between gaming and sleep is well-established, but the role of caffeine has been under-explored.
View Article and Find Full Text PDFChronobiol Int
September 2025
Consultant, Wayzek Science, St Paul, Minnesota, USA.
Understanding how sleep affects the risk of incident chronic conditions in midlife may reinforce the importance of a healthy sleep pattern for healthy aging and cardiometabolic health. The objective of the study was to examine associations of sleep duration and quality with incident obesity, diabetes and metabolic syndrome in mid-aged adults. Participants without obesity ( = 381), diabetes ( = 509), or metabolic syndrome ( = 487) from the Biomarker Projects in Midlife in the United States study were examined separately for baseline sleep duration and quality and their associations with incident obesity, diabetes, or metabolic syndrome after an average follow-up of 12 years.
View Article and Find Full Text PDF