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Thrombectomy significantly improves clinical outcomes in patients with large vessel occlusion. However, the foundational trials used restrictive criteria, excluding patients with prestroke disability and included a few elderly patients (>80 years old). In addition, results from registries demonstrated conflicting results. We propose that there is equipoise for the elderly and prestroke disability to undergo thrombectomy and that trials are urgently required to guide treatment.
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http://dx.doi.org/10.1161/STROKEAHA.124.050299 | DOI Listing |
J Am Med Dir Assoc
September 2025
Irish National Audit of Stroke Care, National Office of Clinical Audit, Dublin, Ireland; St Vincent's University Hospital, Dublin, Ireland.
Objectives: Internationally about 3% of people ≥65 years live in long-term care (LTC) settings. Older people living in nursing homes are more likely to be admitted to hospital. We examined the characteristics and outcomes of stroke patients admitted from LTC nationally and how this changed over the COVID-19 pandemic.
View Article and Find Full Text PDFJ Neurol Sci
August 2025
Department of Neurology, The Affiliated Brain Hospital of Nanjing Medical University, Nanjing, China.; Nanjing Qixia District Hospital, Nanjing. No.28, RaoJia Road, Qixia District, Nanjing, Jiangsu 210046, China.
J Neurol Sci
August 2025
Medical Experiment Center, Shaanxi University of Chinese Medicine, Xianyang 712046, China. Electronic address:
This letter addresses the manuscript titled "Comparison of Prestroke Frailty and Disability for Outcome Prediction in Older Stroke Patients" by Paola Forti et al. The study explores the predictive role of prestroke frailty in stroke outcomes for older patients, demonstrating its potential to guide clinical decision-making. While the large cohort enhances the study's validity, several methodological concerns are raised, including the retrospective use of frailty assessments and the lack of subgroup analyses by stroke type or severity.
View Article and Find Full Text PDFJ Neurol Sci
August 2025
Geriatric Unit, Department of Integrated Care, Ospedale Maggiore, Bologna, Italy.
J Neurol Sci
August 2025
Geriatric Unit, Department of Integrated Care, Ospedale Maggiore, Bologna, Italy.