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Aggression has been reported to be associated with insomnia in adolescents. However, the impact of aggression and different levels of aggression on insomnia needs further exploration. This study aimed to explore the association of aggression, as well as different profiles of aggression, with insomnia in Chinese adolescents. This was a prospective cohort study with an 8-month follow-up period. The Short-Form Buss-Perry Aggression Questionnaire (BPAQ-SF) was used to assess the aggression; the Insomnia Severity Index (ISI) was used to assess the symptoms of insomnia. Latent profile analysis (LPA) was conducted to identify profiles of aggression. The association between different profiles of aggression and insomnia was assessed using logistic regression analysis. We also used the restricted cubic spline model to investigate the pattern of the association. A total of 1124 students completed the questionnaire. The aggression was classified into three profiles: low aggression ( = 931, 82.8%), moderate aggression ( = 153, 13.6%), and high aggression ( = 40, 3.6%). A follow-up survey after 8 months found 228 (20.3%) new cases of insomnia. Moreover, high aggression was associated with a significantly increased risk of insomnia after adjustment for age, sex, ethnicity, anxiety state, and depressive state (odds ratio [OR]: 9.98, 95%CI: 4.94-20.15). The relationship between aggression and the risk of insomnia was linear in the restricted cubic spline regression analysis. High levels of aggression were significantly associated with insomnia among Chinese adolescents. Therefore, targeted interventions aimed at addressing insomnia among adolescents with high levels of aggression are needed to improve their mental well-being.
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http://dx.doi.org/10.1155/da/3713624 | DOI Listing |
Epilepsy Behav
August 2025
MidAtlantic Epilepsy and Sleep, LLC, 6410 Rockledge Drive, #610, Bethesda, MD 20817, USA.
Lennox-Gastaut Syndrome (LGS) is a severe developmental epileptic encephalopathy of childhood consisting of a triad of drug refractory epilepsy with multiple seizure types, cognitive impairment, and a characteristic electroencephalogram (EEG). Cenobamate (CNB) is a novel antiseizure medication (ASM) effective against focal epilepsy. Proposed mechanisms of action include inactivation of persistent sodium currents and weak positive allosteric modulation of synaptic (phasic) and extrasynaptic (tonic) GABAA receptors.
View Article and Find Full Text PDFBMC Public Health
July 2025
Facultad de Medicina, Universidad Continental, Lima, Perú.
Introduction: With the persistence of global challenges related to the COVID-19 pandemic, it has become essential to explore the dynamics of physical activity in adolescents. Although knowledge exists on the importance of physical activity for overall health, understanding the factors influencing adolescent physical activity patterns remains a less explored terrain. This study aims to determine the prevalence and factors associated with physical activity in adolescents in Lambayeque, Peru.
View Article and Find Full Text PDFCancer Epidemiol
July 2025
Department of Hygiene and Epidemiology, School of Medicine, University of Ioannina, Ioannina, Greece; Department of Biostatistics and Epidemiology, School of Public Health, Imperial College London, London, UK.
Background: Sleep traits may influence cancer risk; however, their associations with prostate (PCa), endometrial (ECa), and epithelial ovarian (EOCa) cancer remain unclear.
Methods: We conducted an observational analysis using the UK Biobank cohort and a two-sample Mendelian randomisation (MR) analysis to investigate the association between six sleep traits-duration, chronotype, insomnia, daytime napping, daytime sleepiness, and snoring-with PCa, ECa, and EOCa risk. Cox proportional hazards models were used for the observational analysis, while the inverse variance-weighted (IVW) method was applied in MR, with multiple sensitivity analyses.
Psychopharmacol Bull
July 2025
Alhummayani, Erada and mental health complex, Taif, Saudi Arabia.
Background: Cannabidiol (CBD), a non-intoxicating compound derived from Cannabis sativa, has gained widespread popularity for its proposed therapeutic effects in conditions such as anxiety, insomnia, and chronic pain. Unlike tetrahydrocannabinol (THC), CBD is often perceived as safe, with minimal psychoactive properties. However, its psychiatric safety profile, particularly in relation to mood disorders, remains poorly understood.
View Article and Find Full Text PDFFront Psychiatry
June 2025
Department of Psychiatry, Bozhou People's Hospital, Bozhou, Anhui, China.
Background: Overt aggression may be associated with childhood maltreatment (CM), insomnia, and alexithymia, but the underlying mechanisms of these associations have not been fully explored in adolescents with major depressive disorder (MDD). Therefore, the present study aimed to deeply analyze the relationships between overt aggression and CM, insomnia, and alexithymia in adolescents with MDD, to reveal the mediating mechanisms, and to provide a theoretical basis for clinical interventions.
Methods: From December 2024 to December 2025, this study included 251 adolescents with MDD.