Category Ranking
98%
Total Visits
921
Avg Visit Duration
2 minutes
Citations
20
Article Abstract
Patients with anti-mitochondrial antibody positivity rarely develop tubulointerstitial nephritis with IgM-positive plasma cells (IgMPC-TIN). A previous report observed elevated serum IgM and urinary β2 microglobulin levels in all cases of IgMPC-TIN. This case involved IgA nephropathy with latent coexisting IgMPC-TIN; however, no such changes were observed. These results suggest that some patients with primary biliary cholangitis may have latent IgMPC-TIN without specific urine or blood results. Furthermore, the patient simultaneously developed IgA nephropathy and IgMPC-TIN, suggesting that the triggers and exacerbating factors for both conditions share a common underlying cause.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.2169/internalmedicine.5217-24 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Differential Expression of ATP6V1D and Its Diagnostic Potential in IgA Nephropathy.
Curr Med Sci
September 2025
Department of Agriculture and Biotechnology, Hunan University of Humanities, Science and Technology, Loudi, 417000, China.
Objective: IgA nephropathy (IgAN) is the most prevalent form of primary glomerular disease. However, its diagnosis is contingent on kidney biopsy. Therefore, noninvasive biomarkers are urgently needed for diagnosis.
View Article and Find Full Text PDFIgA Nephropathy Associated Hypertensive Retinopathy and Purtscher-Like Retinopathy.
J Vitreoretin Dis
August 2025
Department of Pathology, Ankara Etlik City Hospital, Ankara, Turkey.
Purtscher-like retinopathy is a condition similar to Purtscher's retinopathy but results from non-traumatic causes. Although its pathophysiology is not fully understood, it is thought to be related to the complement system. Renal diseases, which play a significant role in secondary hypertension, are known to be important in its etiology.
View Article and Find Full Text PDFspecies on the tonsillar surface predicts favorable clinical outcomes in patients with Immunoglobulin A nephropathy who underwent tonsillectomy.
Ren Fail
December 2025
Department of Otolaryngology-Head & Neck Surgery, Asahikawa Medical University, Asahikawa, Japan.
An aberrant mucosal immune response against commensal bacteria in the tonsils is hypothesized to be one of the pathogenic mechanisms underlying immunoglobulin A nephropathy (IgAN). However, the bacteria involved in the pathogenesis of IgAN have not been fully elucidated. In this study, we compared the differences in tonsillar bacterial flora between IgAN ( = 101) and recurrent tonsillitis (RT) ( = 117) based on swab cultures from tonsillar surfaces and the center of the tonsils.
View Article and Find Full Text PDFInvestigating the genetic effects of metformin-related targets on IgA nephropathy using Mendelian randomization.
Ren Fail
December 2025
Department of Gerontology, Zhujiang Hospital, Southern Medical University, Guangzhou, China.
The role of metformin and its downstream targets in IgA nephropathy (IgAN) remains unclear. In this study, we used Mendelian randomization to explore potential causal links between genetic proxies of metformin targets, plasma proteins, and the risk of IgAN. Data on plasma protein, metformin target genes, and IgAN data were obtained from the IEU OpenGWAS Project.
View Article and Find Full Text PDF