Category Ranking
98%
Total Visits
921
Avg Visit Duration
2 minutes
Citations
20
Article Abstract
Rationale And Objectives: To evaluate the technical efficacy and therapeutic outcomes of percutaneous MR-guided thermal ablation, including microwave ablation (MWA) and radiofrequency ablation (RFA) for recurrent subcentimeter hepatocellular carcinomas (HCCs). MATERIALS AND METHODS: From January 2015 to May 2024, we recruited 101 patients with 119 recurrent subcentimeter HCCs (mean diameter: 8.0±1.3 mm, range: 5.6-9.9mm), who were treated with MR-guided thermal ablation. Technical success, technical efficacy, complications, and local tumor progression (LTP) rate were evaluated after ablation. Cumulative LTP rate, recurrence-free survival (RFS), and overall survival (OS) rates were estimated using the Kaplan-Meier method.
Results: A retrospective analysis showed that MR-guided thermal ablation (MWA, n=84; RFA, n=17) was successfully executed in all cases. Technical success and efficacy were achieved in all lesions in single sessions without major complications. The mean follow-up duration was 41.1±27.1 months (median:38.0 months; range:3-105 months). The cumulative LTP rate at 1 year was 1.2%, and 5.8% at 3, 5, 7, and 9 years. The cumulative RFS rates at 1, 3, 5, 7, and 9 years were 82.2%, 44.6%, 29.0%, 23.2%, and 23.2%, respectively. The cumulative OS rates at 1, 3, 5, 7, and 9 years were 99.0%, 91.8%, 84.4%, 69.7%, and 62.0%, respectively.
Conclusion: Percutaneous MR-guided thermal ablation for recurrent subcentimeter HCCs demonstrated ready visualization of lesions and ablation margins as well as high technical efficacy rate, and minimal LTP after a single treatment session.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1016/j.acra.2025.04.053 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
The use of alendronate to enhance transcranial transmission of focused ultrasound for successful ablations in brain.
Ultrasonics
August 2025
Lomonosov Moscow State University, Leninskiye Gory 1/2, Moscow, 119992, Russia.
Objective: The aim of this study was to evaluate the efficacy of alendronate therapy in improving bone density distribution in skull bones and corresponding ultrasound permeability in patients who had previously experienced unsuccessful transcranial MR-guided focused ultrasound (MRgFUS) ablation. The ability of alendronate treatment to modify skull bone characteristics and enhance the success rate of repeat MRgFUS procedures was assessed.
Methods: Five patients with initially unsuccessful MRgFUS ablations underwent a 6-12 month regimen of alendronate to improve bone density.
Intraoperative and long-term multimodal radiological assessment of brain MR-guided laser interstitial thermal therapy (MRgLITT) in children.
J Neuroradiol
August 2025
Pediatric Radiology Department, AP-HP, Hôpital Universitaire Necker-Enfants Malades, F-75015 Paris, France; Université Paris Cité, INSERM U1299, F-75015 Paris, France; Université Paris Cité, UMR 1163, Institut Imagine, F-75015 Paris, France; Paris Kids Cancer. Electronic address: volodia.dangou
Objectives: Magnetic resonance-guided laser interstitial thermal therapy (MRgLITT) has emerged as a minimally invasive alternative for drug-resistant epilepsy and pediatric brain tumors, particularly in deep-seated lesions where open surgery presents significant risks. However, the multimodal imaging characteristics of lesions during and after MRgLITT remain underexplored. This study aims to describe the MRI features of MRgLITT-treated lesions in pediatric patients both intraoperatively and during long-term follow-up.
View Article and Find Full Text PDFNavigating the Landscape of Uterine Fibroid Treatment Using a Novel Scarless Technology (GYIDE): A Case Report.
Gynecol Minim Invasive Ther
July 2025
Department of Research and Development, Nesa Medtech Pvt. Ltd., Bengaluru, Karnataka, India.
Uterine fibroids (UFs) affect 70%-80% of women by age 50. Traditional treatments include medical management and invasive surgery. Recent advancements in fibroid treatment introduce less invasive methods like radiofrequency ablation (RFA), microwave ablation, uterine artery embolization, and MR-guided focused ultrasound.
View Article and Find Full Text PDFSkull Lesions Following MR-Guided High-Intensity Focused Ultrasound: A Case Series.
AJNR Am J Neuroradiol
August 2025
From the School of Medicine (N.H.D.), University of Colorado Anschutz Medical Campus, Aurora, Colorado; Departments of Neurology (D.S.K., S.G.O.), Neurosurgery (D.S.K., S.G.O.), and Radiology (J.M.H., J.L.T.), University of Colorado Anschutz Medical Campus, Aurora, Colorado.
Transcranial MR-guided high-intensity focused ultrasound (HIFUS) ablation is a therapeutic modality for essential tremor and tremor-dominant Parkinson's disease. Skull marrow lesions may occur post-treatment and mimic metastatic disease. In this retrospective study of 10 patients receiving a delayed post-treatment MRI, four patients developed skull lesions.
View Article and Find Full Text PDFBackground: In the fifteen years since the first patient with drug-resistant epilepsy was treated by MR - guided laser interstitial thermal therapy (LITT) it has revolutionized the surgical treatment of epilepsy. Therapeutic targets have ranged from every form of epileptogenic lesion, including mesial temporal sclerosis (MTS), hypothalamic hamartomas (HH), malformations of cortical development, low-grade epilepsy associated tumors, and cerebral cavernous malformations (CCM), to MRI-normal epileptogenic zones characterized by stereo-electroencephalography (SEEG), to disconnection surgeries such as corpus callosotomy and even functional hemispherotomy. Many series now support the general effectiveness and safety of LITT for epilepsy although we are still in the period where increasing experience and technical advances are driving refinement in the therapy.
View Article and Find Full Text PDF