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Objectives: To determine the effect of structured myofascial release techniques on symptoms in individuals with primary dysmenorrhea.
Material And Methods: Based on an expected effect size (d = 0.25), α = 0.05, β = 0.20, a minimum of 36 participants was calculated using G*Power for 80 % power. Although 52 were targeted considering 30 % attrition, 41 completed the study. We enrolled 41 participants with PD who were randomly classified into three groups: Structured myofascial release (MFG), transcutaneous electrical nerve stimulation (TENS) and training. All participants were evaluated 3 times: 1st measurement on the first day of the menstrual cycle (pre), 2nd measurement after treatment (post) and 3rd measurement 4 weeks after treatment (follow-up). Outcome measures; demographic information, McGill Pain Questionnaire Short Form, Menstruation Symptom Questionnaire (MSQ), Functional and Emotional Measure of Dysmenorrhea (FEMD), and VAS questionnaire were applied. Pain threshold and muscle tension were measured.
Results: While a significant difference was detected between the pre-post and pre-follow-up values in the pairwise comparisons of MC-1, MC-2, MC-3, and MC-4 values in the MFG group, a significant difference was detected between the pre-post and pre-follow-up MC-1, MC-2, and MC-4 values in the TENS and training groups (p < 0.05). Key outcome differences included a 30 % reduction in MPQ-SF scores in the MFG group (p < 0.001). In all groups, a significant difference was found between the three time-dependent measurements of the MSQ and FEMD values (Pre, Post, Follow-up) (p < 0.05). The mean Follow-up Myoton was 3.63 ± 0.33 in the MFG group, 4.49 ± 0.49 in the TENS group and 4.89 ± 0.57 in the Training group. A significant difference was found between the three time-dependent measurements of Myoton and VAS values (Pre, Post, and Follow-up of the individuals in the MFG group) (*F = 46.600; *χ2 = 25.739; p < 0.001).
Conclusions: The MFG group demonstrated superior efficacy to the TENS and training groups in alleviating dysmenorrheic pain, enhancing pain threshold, reducing dysmenorrhea symptoms, and decreasing lower abdominal tension. This effect persisted during the follow-up period, 4 weeks post-treatment.
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http://dx.doi.org/10.1016/j.ejogrb.2025.114025 | DOI Listing |
J Mech Behav Biomed Mater
August 2025
Mechanical and Aerospace Engineering, School of Engineering and Applied Science, University of Virginia, Charlottesville, VA, USA; Systems and Information Engineering, School of Engineering and Applied Science, University of Virginia, Charlottesville, VA, USA. Electronic address:
Soft tissue manipulation is used widely to assess myofascial tissue qualitatively but lacks objective measures. To quantify the mobility of myofascial tissue, this effort derives optical biomarkers from the skin surface, as observed in the hands-on workflow of clinicians. Digital image correlation using three high-resolution cameras captures the cervicothoracic region as a clinician deeply engages and stretches the skin and myofascial tissue.
View Article and Find Full Text PDFFree Radic Biol Med
August 2025
Department of School of Medicine, Nankai University, Tianjin, 300071, China; Department of Anesthesiology, Tianjin First Central Hospital, Tianjin, 300380, China. Electronic address:
Background And Aims: Myofascial pain syndrome (MPS), driven by dysfunction in myofascial trigger points (MTrPs), remains mechanistically unclear. This study aimed to explore miR-15 b's function in MTrP pathogenesis, focusing on its regulation of iron-sulfur (Fe-S) cluster synthesis and mitophagy.
Methods: A rat MTrP model was established using repetitive mechanical injury and eccentric exercise.
Life (Basel)
July 2025
Department of Neuroscience, Institute of Human Anatomy, University of Padova, 35141 Padova, Italy.
In recent years, the concept of the myofascial network has transformed biomechanical understanding by emphasizing the body as an integrated, multidirectional system. This study advances that paradigm by applying graph theory to model the osteo-myofascial system as an anatomical network, enabling the identification of topologically central nodes involved in force transmission, stability, and coordination. Using the aNETomy model and the BIOMECH 3.
View Article and Find Full Text PDFCureus
August 2025
Department of Dentistry and Oral Surgery, Keio University School of Medicine, Tokyo, JPN.
Background and objective Musculoskeletal factors, such as myofascial pain, are often overlooked in chronic headaches. This study aimed to evaluate the effectiveness of a structured self-care program, myofascial pain management (MPM), for patients with chronic headaches. Methods This single-arm observational study involved 37 patients with chronic headaches who were referred from a neurology clinic.
View Article and Find Full Text PDFCureus
July 2025
Department of Fixed Prosthodontics, Faculty of Dentistry, Hassan II University, Casablanca, MAR.
Temporomandibular disorder (TMD) is a complex, multifactorial disorder affecting the masticatory muscles, the temporomandibular joint, and associated structures. These disorders are also associated with other symptoms affecting the head and neck region, such as headaches, ear-related symptoms, cervical spine dysfunction, and altered head and neck posture. TMDs require multidisciplinary care.
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