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Diet has a profound impact on brain health, particularly in middle-aged and older adults, who are at increased risk of cognitive decline and neurodegenerative diseases. Various dietary patterns, including the Mediterranean diet (MedDiet), Dietary Approaches to Stop Hypertension (DASH), and Mediterranean-DASH Intervention for Neurodegenerative Delay (MIND) diets, have been linked to improved cognitive function. While the relative effectiveness of these diets on brain health is generally supported by evidence, variability in study results suggests that further research is needed to fully understand their effects across diverse populations. The objective of this descriptive narrative review is to examine the role of dietary patterns in supporting brain health in aging populations and to propose practical dietary strategies for promoting cognitive well-being. A comprehensive review of the existing literature was conducted on PubMed in October 2024, with no restrictions on language, publication date (1966-2024), or geographic location. A total of 18 articles were included in this review, covering the years 2013-2023. Studies assessing the impact of the MedDiet, DASH, MIND, and Western diets on cognitive function in middle-aged and older adults were prioritized. The research findings were synthesized to identify common and unique recommendations across these dietary patterns. The MedDiet consistently showed beneficial effects on cognitive health, including improved memory, processing speed, and long-term protection against neurodegenerative conditions. The DASH and MIND diets demonstrated potential benefits, particularly for specific cognitive domains, but the results were more mixed and inconclusive. In contrast, adherence to a Western diet was associated with negative cognitive outcomes, including cognitive decline and smaller brain volumes. These findings underscore the importance of adopting healthy dietary patterns as a modifiable lifestyle factor to support cognitive aging and inform future public health strategies and clinical guidelines.
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http://dx.doi.org/10.3390/nu17091436 | DOI Listing |
Int J Food Sci Nutr
September 2025
Department of BSc (Hons) Dietetics, Metropolitan College, Athens, Greece.
The present study explored associations between the five personality traits (Extraversion, Agreeableness, Conscientiousness, Neuroticism, and Openness) and dietary patterns of apparently healthy individuals. Demographic, anthropometric, dietary, and personality data were obtained from 480 adults, up to 45 years of age, through self-completed questionnaires. Dietary habits were assessed a validated for the population Food Frequency Questionnaire (FFQ), whereas personality was evaluated with the validated Greek version of the 50-item International Personality Item Pool (IPIP).
View Article and Find Full Text PDFJ Lipid Res
September 2025
Department of Surgery, University of California Davis School of Medicine, Sacramento, CA, USA; Center for Alimentary and Metabolic Science, University of California Davis School of Medicine, Sacramento, CA, USA. Electronic address:
Cyclopropane fatty acids (CpFAs) are members of the mammalian lipidome, originating from the diet and gut microbial metabolism. Despite being fully saturated, conformational modeling of CpFAs from C12 to C24 in length revealed that they are bent lipids sharing structural similarities with monounsaturated fatty acids (MUFAs). We therefore hypothesized that CpFAs might share some bioactivities with MUFAs.
View Article and Find Full Text PDFJ Nutr Biochem
September 2025
Multicentric Postgraduate Program in Physiological Sciences, SBFis, São Paulo State University (UNESP), School of Dentistry, Araçatuba, SP, Brazil; Department of Basic Sciences, São Paulo State University (UNESP), School of Dentistry, Araçatuba, SP, Brazil; Postgraduate Program in Sciences, Pedi
Studies indicate that dietary patterns influence the function and redox balance of salivary glands. This study examined the effects of intermittent fasting (IF) on the function, histological structure, and redox balance of the salivary glands. Twenty 12-weeks-old male Wistar rats were randomized into two groups: ad libitum (AL), with continuous access to water and chow, and IF, subjected to 24-hour fasting on alternate days for 12 weeks.
View Article and Find Full Text PDFNutr Clin Pract
September 2025
School of Biological, Health and Sports Sciences, Technological University Dublin, Dublin, Ireland.
Background: Esophagectomy causes anatomical changes that can lead to rapid food transit and reactive hypoglycemia (RH). Patients are advised on eating patterns postesophagectomy to prevent RH, but its true incidence and the impact of dietary recommendations remain under-researched.
Materials And Methods: Individuals >12 months postesophagectomy were recruited from the National Centre for Oesophageal and Gastric Cancer at St James's Hospital in Dublin, Ireland.
J Nutr
September 2025
School of Medicine and Allied Health Sciences, University of The Gambia, Banjul, The Gambia; Shandong Provincial Key Laboratory of Precision Oncology, Shandong Cancer Hospital and Institute, Shandong First Medical University & Shandong Academy of Medical Sciences, 440 Jiyan Road, Jinan, Shandong 250
Background: Red and processed meat consumption is extensively linked to chronic disease risk in observational studies, with robust meta-analyses demonstrating significant positive associations for colorectal, breast, endometrial, and lung cancers, type 2 diabetes (T2DM), cardiovascular disease (CVD), and all-cause mortality. Dose-response relationships indicate elevated risks even at moderate intakes. Moreover, processed meats consistently show stronger detrimental effects than unprocessed red meats.
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