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Objectives: This study investigated the association between the level of engagement in cognitive activities and the risk of incident dementia among community-dwelling older adults with social frailty.
Study Design: This prospective cohort study included 2725 adults aged 60 or more without dementia at baseline.
Main Outcome Measures: Social frailty was based on five items: living alone, going out less frequently than in the previous year, not visiting friends, not feeling useful to family and friends, and not conversing with someone every day. Participants meeting two or more of these criteria were defined as having social frailty. Cognitive activities comprised 12 items according to the frequency of implementation. Four groups were created by combining social frailty status and cognitive activity levels. The Cox proportional hazards model was used to analyze the relationship between the combination of social frailty and cognitive activity and the incidence of dementia at 60 months.
Results: Compared with the group without social frailty and with high engagement in cognitive activity, the group with social frailty and low engagement had a significantly higher risk of dementia. However, the former group showed a reduction in the risk of dementia.
Conclusions: High engagement in cognitive activities was found to be associated with a reduced risk of dementia, even in the context of social frailty. Cognitive activities that are feasible for solitary execution have the potential to benefit older adults experiencing challenges with social participation.
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http://dx.doi.org/10.1016/j.maturitas.2025.108597 | DOI Listing |
Ann Geriatr Med Res
September 2025
Institute of Health and Sport Sciences, University of Tsukuba, 1-1-1 Tennodai, Tsukuba, Ibaraki, Japan.
Background: Poor hand dexterity may increase the risk of functional disability; however, few studies have examined the relationship between hand dexterity and incident functional disability. The aim of this study was to prospectively investigate the dose-response association of hand dexterity with incident functional disability in community-dwelling older adults.
Methods: This study included 1,069 older adults aged ≥65 years in Kasama City, Japan.
Health Expect
October 2025
Yorkshire Quality and Safety Research Group, Bradford Institute for Health Research, Bradford Teaching Hospitals NHS Foundation Trust, Bradford, UK.
Background: Older people face numerous challenges when managing multiple medicines. They are required to cope with complicated and changing medicines regimens and coordinate input from multiple health and social care professionals. When not well managed, medicines can cause harm, and older people are more susceptible to the impact of errors.
View Article and Find Full Text PDFArch Gerontol Geriatr
August 2025
Institute of Gerontology, The University of Tokyo, Hongo 7-3-1, Bunkyo-ku, Tokyo 113-8656, Japan; Institute for Future Initiatives, The University of Tokyo, Hongo 7-3-1, Bunkyo-ku, Tokyo 113-8656, Japan. Electronic address:
A frailty checkup program (FC), a community-based frailty prevention initiative led by trained senior volunteers (FC supporters), has been implemented in over 100 municipalities in Japan. Participants create individual result sheets by marking blue signals for positive responses and red signals for negative responses. This cohort study aimed to examine the association between FC results and the risk of incident disability and mortality among community-dwelling older adults.
View Article and Find Full Text PDFAgeing Res Rev
September 2025
University of Antwerp - Faculty of Medicine and Health Sciences - Department of Rehabilitation Sciences and Physiotherapy - Research Group MOVANT, Antwerp, Belgium; Vrije Universiteit Brussel - Faculty of Physical Education and Physiotherapy - Department Physiotherapy, Human Physiology and Anatomy -
Introduction: Frailty in older adults impairs Activities of Daily Living (ADL). While exercise interventions improve factors like muscle strength and physical function, their direct impact on ADL ability is inconsistent. This review aims to assess the effectiveness of exercise on ADL ability, identify the most beneficial interventions, and explore mediators.
View Article and Find Full Text PDFAging Clin Exp Res
September 2025
Department of Cardiovascular Medicine and Hypertension, Graduate School of Medical and Dental Sciences, Kagoshima University, Kagoshima, Japan.
Background: Intrinsic capacity (IC) and frailty are distinct but complementary frameworks for understanding the heterogeneity of aging. Although both have been linked to self-rated health, little is known about how their combined status relates to older adults’ health perceptions. This cross-sectional study investigated how combinations of IC and frailty status were associated with self-rated health among community-dwelling older adults.
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