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Background: Valid, sensitive healthy diet metrics that are comparable across contexts are needed for global monitoring. The healthy diets monitoring initiative identified 4 field metrics as potentially fit for purpose: global diet quality score (GDQS), global dietary recommendations score, minimum dietary diversity for women (MDD-W), and Nova ultra-processed food score.
Objectives: To review whether these 4 healthy diet metrics ) accurately predict food and nutrient intakes; ) accurately differentiate the average or prevalence of food and nutrient intakes; ) respond to changes over time; ) are comparable across contexts; and ) can be collected using their proposed brief assessment methods while preserving predictive accuracy.
Methods: Peer-reviewed literature was searched and extracted from PubMed, Web of Science, and Google Scholar, including preprints and grey literature from the latter. Evidence on the accuracy of the field metrics and methods was qualitatively assessed against the aforementioned objectives, considering the underlying theory of change and study design, as well as the direction and magnitudes of the observed associations or effects.
Results: Increments in GDQS+ and MDD-W predicted higher composite metrics of nutrient adequacy. MDD-W was sensitive to changes in nutrient intakes over time. MDD-W cutoffs showed limited variability across contexts and population groups. Higher GDQS and global dietary recommendation scores and lower Nova ultra-processed food scores were associated with lower intakes of food and nutrients to moderate. The predictive accuracy of field methods for nutrient adequacy was maintained for GDQS and MDD-W. No study explicitly investigated how field metrics differentiate averages or prevalence of reference metrics across countries.
Conclusions: MDD-W demonstrated comparatively stronger predictive accuracy for nutrient adequacy, with a lower burden method, than GDQS+. Further research is required to determine the predictive accuracy of field-friendly metrics measuring moderation across contexts and time. Complementary metrics that can be collected simultaneously on a large scale are needed for global monitoring.
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http://dx.doi.org/10.1016/j.cdnut.2025.107439 | DOI Listing |
Clin J Am Soc Nephrol
September 2025
Division of Nephrology, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland USA.
Socioeconomic, environmental and lifestyle factors shape kidney health. Among the social determinants of health, access to healthy foods is particularly significant. As a basic need, food is integral to an individual's identity, culture, and health.
View Article and Find Full Text PDFHigh Blood Press Cardiovasc Prev
September 2025
Center for Translational and Experimental Cardiology, Department of Cardiology, University Hospital Zurich and University of Zürich, Wagistrasse 12, 8952, Schlieren, Switzerland.
Introduction: Epigenetic changes are important modulators of gene expression. The histone acetyltransferase gene non-derepressible 5 (Gcn5) is emerging as a pivotal epigenetic player in metabolism and cancer, yet its role in obesity and cardiovascular disease remains elusive.
Aims: To investigate Gcn5 role in obesity-related endothelial dysfunction.
Graefes Arch Clin Exp Ophthalmol
September 2025
Department of Physics of Condensed Matter, Optics Area. Vision Research Group (CIVIUS), University of Seville, Avenida de la Reina Mercedes s/n (41012), Seville, Spain.
Purpose: To analyze the relationship between various visual function parameters (refractive status, visual acuity and contrast sensitivity) and macular pigment optical density (MPOD) values, as well as dietary intake of lutein and zeaxanthin in a pediatric population.
Methods: Thirty-six healthy White pediatric patients participated in this cross-sectional study conducted at the Optometry Clinic (Faculty of Pharmacy, Seville, Spain). MPOD values were measured using the MPSII (Macular Pigment Screener II).
Cancer Rep (Hoboken)
September 2025
Student Research Committee, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran.
Background And Aims: Breast cancer is the most commonly diagnosed cancer in women worldwide. Several studies have investigated the relationship between breast cancer and specific foods or nutrients, rather than examining an overall dietary pattern. This study aims to investigate the association between breast cancer and the predominant dietary pattern in Ahvaz city.
View Article and Find Full Text PDFAdv Pharm Bull
July 2025
Division of Biological and Health Sciences, University of Pittsburgh at Bradford, Bradford, PA, United States.
The prevalence of nutrition-related non-communicable diseases like diabetes mellitus (DM) is exponentially increasing across the world. Particularly, type-2 diabetes mellitus (T2DM) is prevalent in sub-Saharan Africa (SSA) than in any other region of the world, with a significant effect on mortality and morbidity. T2DM is a disease known to be associated with elevated glucose levels in the blood, caused by numerous factors including dietary and lifestyle changes.
View Article and Find Full Text PDF