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Mechanical metamaterials can unlock extreme properties by leveraging lightweight structural design principles and unique deformation mechanisms. However, research has predominantly focused on their quasi-static characteristics, leaving their behavior under extreme dynamic conditions, especially at length scales relevant to practical applications largely unexplored. Here, we present a strategy to achieve extreme impact mitigation at the macroscale by combining shell-based microarchitecture with an additively manufactured medium-entropy alloy (MEA) featuring low stacking fault energy (SFE). Notably, the shell-based architecture amplifies the effective dynamic stress within the metamaterial compared to truss-based morphologies, leading to the earlier activation of multiscale toughening mechanisms in the alloy. The low SFE of the MEA enables the evolution of a diverse array of defect types, thereby prolonging strain hardening behavior across seven orders of magnitude in strain rate. These fundamental insights could establish the groundwork for developing scalable, lightweight, impact-resistant metamaterials for structural and defense applications.
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC12057667 | PMC |
http://dx.doi.org/10.1126/sciadv.adt0589 | DOI Listing |
Kardiologiia
September 2025
Almazov National Medical Research Center, St. Petersburg.
Fulminant myocarditis is characterized by an extremely severe course and remains a life-threatening disease. Only isolated cases of diffuse myocardial calcification in myocarditis have been reported. For this reason, the process of natural evolution of myocardial structural changes and their impact on the cardiovascular system have not yet been sufficiently studied.
View Article and Find Full Text PDFGlob Chang Biol
September 2025
European Centre for Medium-Range Weather Forecast (ECMWF), Reading, UK.
The catastrophic Los Angeles Fires of January 2025 underscore the urgent need to understand the complex interplay between hydroclimatic variability and wildfire behavior. This study investigates how sequential wet and dry periods, hydroclimatic rebound events, create compounding environmental conditions that culminate in extreme fire events. Our results show that a cascade of moisture anomalies, from the atmosphere to vegetation health, precedes these fires by around 6-27 months.
View Article and Find Full Text PDFInt J Pediatr
August 2025
Department of Neonatology, Asfendiyarov Kazakh National Medical University, Almaty, Kazakhstan.
This study is aimed at evaluating the cumulative effect of postnatal risk factors on the survival of preterm neonates by examining key clinical parameters and complications across various gestational ages. A retrospective cohort study was conducted using data from 1109 neonates admitted to neonatal intensive care units at two tertiary regional hospitals in Kazakhstan between 2021 and 2024. Patients were classified into three groups based on gestational age: extremely preterm (< 28 weeks, = 223), very preterm (28-31 weeks, = 384), and moderate to late preterm (32-36 weeks, = 502).
View Article and Find Full Text PDFFront Public Health
September 2025
Department of Environmental Health, Harvard T. H. Chan School of Public Health, Boston, MA, United States.
The frequency and severity of heat waves are expected to worsen with climate change. Exposure to extreme heat, or prolonged unusually high temperatures, are associated with increased morbidity and mortality. The fetus, infant, and young child are more sensitive to higher temperatures than older children and most adults given that they are rapidly developing.
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