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http://dx.doi.org/10.1016/j.hrcr.2024.09.020 | DOI Listing |
Lab Anim
August 2025
Institute for Biological and Chemical Systems-Biological Information Processing (IBCS-BIP), Karlsruhe Institute of Technology, Germany.
The use of zebrafish as an animal model for biomedical and toxicological research has increased dramatically over the past decade, alongside a growing need to adopt the 3Rs principles to ensure ethically acceptable animal experimentation. Currently, one of the main challenges concerns 'surplus' animals that are unavoidably generated as part of an experimental procedure and are unsuitable for experimental analysis because they do not have the desired genotype, are too old or have the wrong sex. However, justifying the sacrifice of animals for these reasons is morally debatable and current ethics legislation in some countries insists they should nevertheless be maintained and left to die of natural causes.
View Article and Find Full Text PDFZ Gastroenterol
August 2025
Gastroenterology, Gastrointestinal Oncology and Endocrinology, University Medical Center Göttingen, Göttingen, Germany.
Perisplenic masses or collections are rare findings on imaging examinations. The differential diagnostic spectrum is broad. We report the case of an 84-year-old man who presented to our emergency department with fatigue, unwanted weight loss, loss of appetite and abdominal pain.
View Article and Find Full Text PDFExtensive research has demonstrated that people can intentionally forget by inhibiting the retrieval of unwanted memories, a phenomenon known as suppression-induced forgetting (SIF). Although neuroimaging studies have linked retrieval suppression to the right lateral prefrontal cortex (LPFC), direct evidence for the causal role of this region plays in supporting SIF is still lacking. In this registered report, our aim is putting to a strong empirical test such an idea by using cathodal transcranial direct current stimulation in a standard think/no-think procedure.
View Article and Find Full Text PDFWorld J Gastrointest Oncol
May 2025
Department of Gastroenterology and Hepatology, University Medical Center Utrecht, Utrecht 3584 CX, Utrecht, Netherlands.
Cryotherapy is a treatment modality that uses extreme cold to destroy unwanted tissue through both immediate and delayed cellular injury. This therapy is increasingly being adopted across various medical specialties due to its minimally invasive nature and technological advancements that have been made. In the esophagus, cryotherapy is particularly utilized for the management of Barrett esophagus.
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