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http://dx.doi.org/10.1016/j.ijcard.2025.133355 | DOI Listing |
Curr Cardiol Rev
August 2025
Department of Cardiology, University of Central Florida, Orlando, FL, USA.
Introduction: Acute myocardial infarction is a significant global health issue, with a high mortality rate. Early intervention, specifically coronary angiography, has been shown to improve patient outcomes significantly. Recent technological advances have introduced novel therapeutic interventions like Supersaturated Oxygen (SSO2) Therapy, which promises enhanced recovery post-ischemia.
View Article and Find Full Text PDFInt J Mol Sci
July 2025
Instituto do Coração, Faculdade de Medicina, Universidade de São Paulo (InCor/HCFMUSP), São Paulo 05403-900, Brazil.
Coronary microvascular obstruction and dysfunction (CMVO) frequently arise following primary percutaneous coronary intervention (PCI), particularly in individuals with myocardial infarction. Despite the restoration of epicardial blood flow, microvascular perfusion might still be compromised, resulting in negative clinical outcomes. CMVO is a complex condition resulting from a combination of ischemia, distal thrombotic embolization, reperfusion injury, and individual susceptibilities such as inflammation and endothelial dysfunction.
View Article and Find Full Text PDFCardiol Rev
July 2025
From the New York Medical College, School of Medicine, Valhalla, NY.
Supersaturated oxygen (SSO2) therapy is a treatment modality that is gaining further attention and consideration for patients with coronary artery disease (CAD). SSO2 therapy is meant to be utilized as an adjuvant therapy with primary percutaneous coronary intervention to treat CAD. Animal models, particularly swine models, have been invaluable in demonstrating the potential benefits SSO2 therapy holds for treating CAD and myocardial infarction.
View Article and Find Full Text PDFMembranes (Basel)
July 2025
AAU Energy, Aalborg University, 9220 Aalborg, Denmark.
The crossover of the product gases hydrogen and oxygen in alkaline electrolyzer operation is a critical factor, severely limiting the operational window in terms of current density and pressure. In prior experiments, it was found that a large degree of oversaturation of the reaction products in the liquid electrolyte phase leads to high amounts of crossover. We are proposing to reduce this amount of oversaturation by introducing micro-cracks in the Zirfon diaphragm.
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