98%
921
2 minutes
20
Download full-text PDF |
Source |
---|---|
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC12061744 | PMC |
http://dx.doi.org/10.3803/EnM.2025.2403 | DOI Listing |
J Biomed Mater Res B Appl Biomater
September 2025
Fertility and Infertility Research Center, Health Technology Institute, Kermanshah University of Medical Sciences, Kermanshah, Iran.
In the current in vitro experiment, we fabricated and characterized placenta/platelet-rich plasma (PL/Pt) composite scaffolds and evaluated their effect on differentiating adipose stem cells (ASCs) into insulin-producing cells (IPCs) in vitro. The human placenta (PL) was decellularized (dPL), characterized, and digested in pepsin. PRP was extracted using a two-step centrifugation process and then freeze-dried.
View Article and Find Full Text PDFJ Clin Lipidol
June 2025
Department of Endocrinology, Medical University Sofia, Sofia, Bulgaria (Drs Dimova, Chakarova, Serdarova, Kirilov, and Tankova).
Background: The aim of this study was to determine the ceramide subspecies profile in people with impaired 1-hour or 2-hour postload glucose during a 75 g oral glucose tolerance test (OGTT) and their association with cardiometabolic parameters.
Methods: Out of 90 subjects (age 46.7 ± 10.
Am J Physiol Endocrinol Metab
August 2025
"Aldo Ravelli" Center for Neurotechnology and Experimental Brain Therapeutics, Department of Health Sciences, Università degli Studi di Milano, Milan, Italy.
Cystic Fibrosis (CF) is a genetic disease that primarily affects the pancreas and lungs. CF dyslipidaemia is characterized by decreased circulating lipids and increased ectopic lipid deposition in liver, pancreas, and lungs. Pancreatic exocrine insufficiency precedes the onset of CF related diabetes (CFRD).
View Article and Find Full Text PDFDiabetol Metab Syndr
August 2025
Department of Pharmacy, Shiraz University of Medical Sciences, Shiraz, Iran.
Background: Imeglimin as a novel antidiabetic agent has emerged promising effects compared to previously established treatments. This updated systematic review and meta-analysis and umbrella review evaluated the efficacy and safety of Imeglimin in managing Type 2 Diabetes Mellitus (T2DM).
Methods: A systematic search of PubMed, Scopus, Web of Science, Embase, and Cochrane Central was conducted up to June 2025.
Acta Diabetol
August 2025
Jiangsu Institute of Clinical Immunology, The First Affiliated Hospital of Soochow University, 178 Ganjiang East Road, Suzhou, 215000, China.
Aims: Autoreactive memory T cells are considered to be a primary contributor to chronic islet inflammation in individuals with type 1 diabetes (T1D). OX40-expressing T cells not only facilitate and sustain the presence of CD4 memory T cells but also promote the generation of CD8 memory T cells. We aimed to investigate the role of OX40CD4/CD8 memory T lymphocytes in the pathogenesis of T1D.
View Article and Find Full Text PDF