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Objectives: Early surgical intervention within 48 h is critical for reducing mortality and morbidity in patients with hip fractures. However, occult hip fractures are often missed, leading to treatment delays. Dual-energy computed tomography allows visualization of bone marrow edema and bone contusions, which are challenging to detect using conventional computed tomography. This study aimed to evaluate the effectiveness of dual-energy computed tomography in diagnosing occult hip fractures.
Methods: Eighteen dual-energy computed tomography scans obtained between May 2018 and March 2024 were analyzed. Magnetic resonance imaging was performed in all cases. A trained musculoskeletal radiologist interpreted the dual-energy computed tomography and magnetic resonance imaging scans, which were then reviewed by two senior orthopedic surgeons. The confirmed diagnoses included 14 femoral trochanteric fractures and 4 femoral neck fractures. Four junior orthopedic surgeons independently reviewed the dual-energy computed tomography scans only and conducted diagnostic examinations. Patients were subsequently categorized into two groups: those with unanimous diagnostic agreement (unanimity group) and those with discrepancies (objection group).
Results: For femoral trochanteric fractures, sensitivity, specificity, accuracy, and Cohen's kappa coefficient were 94%, 81%, 0.91, and 0.75, respectively. For femoral neck fractures, sensitivity, specificity, accuracy, and Cohen's kappa coefficient were 68%, 96%, 0.90, and 0.69, respectively. A significant difference in diagnostic ease was noted ( = 0.04), with agreement achieved for 12 of the 14 femoral trochanteric fractures and one of the four femoral neck fractures. Logistic regression analysis yielded a regression coefficient for femoral trochanteric fractures of 3.05 ( = 0.03), indicating that these fractures were more easily diagnosed than femoral neck fractures.
Conclusions: Dual-energy computed tomography demonstrated high sensitivity and specificity in detecting occult hip fractures, particularly those of the femoral trochanter. However, its sensitivity was lower for femoral neck fractures, indicating limited reliability in their diagnosis. Further investigation and magnetic resonance imaging scans are recommended for suspected femoral neck fractures.
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http://dx.doi.org/10.1177/20503121251336301 | DOI Listing |
Ann Intern Med
September 2025
Department of Medicine, St Michael's Hospital, University of Toronto, Toronto, Ontario, Canada (J.G.R.).
Background: Animal studies show ovarian follicle damage and mutagenesis after ionizing radiation exposure. Computed tomography (CT) imaging is commonly done outside pregnancy, but risks to future pregnancy are unknown.
Objective: To evaluate the risk for spontaneous pregnancy loss and congenital anomalies in offspring of women exposed to CT ionizing radiation before conception.
Ann Intern Med
September 2025
Associate Professor of Radiology, Penn State Health, Hershey, Pennsylvania.
J Infect Dev Ctries
August 2025
Department of Emergency, Changhai Hospital, Naval Medical University, Shanghai, China.
Introduction: Nocardia spp. are Gram-positive, aerobic actinomycetes, which can cause pulmonary, primary cutaneous, and lymphocutaneous infections. However, severe pneumonia caused by Nocardia otitidiscaviarum has rare reported.
View Article and Find Full Text PDFPLoS One
September 2025
Department of Radiology, the Third Affiliated Hospital of Kunming Medical University, Yunnan, Kunming, China.
Purpose: Bronchiolar adenoma (BA) is a rare benign pulmonary neoplasm originating from the bronchial mucosal epithelium and mimics lung adenocarcinoma (LAC) both radiographically and microscopically. This study aimed to develop a nomogram for distinguishing BA from LAC by integrating clinical characteristics and artificial intelligence (AI)-derived histogram parameters across two medical centers.
Methods: This retrospective study included 215 patients with diagnoses confirmed by postoperative pathology from two medical centers.
JAMA Neurol
September 2025
Department of Radiology, University of Washington, Seattle.
Importance: Recent longitudinal studies in patients with unruptured intracranial aneurysms (UIAs) suggested that aneurysm wall enhancement (AWE) on magnetic resonance imaging (MRI) predicts growth and rupture. However, because these studies were limited by small sample size and short follow-up duration, it remains unclear whether this radiological biomarker has predictive value for UIA instability.
Objective: To determine the 4-year risk of instability of UIAs with AWE and investigate whether AWE is an independent predictor of UIA instability.